Fatal methadone intoxication in an infant

Couper, Fiona J.; Chopra, Kiran; Pierre-Louis, Marie

doi:10.1016/j.forsciint.2005.04.014

Cited by 41 publications

(26 citation statements)

References 5 publications

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“…Although non-fatal poisoning of children by methadone is well recognised only a small number of deaths in infants and older children attributed to methadone toxicity have been reported in the literature [2][3][4][5][6][7][8][9][10]. Cases of methadone related poisoning and/or fatalities have been reviewed previously [11,12].…”

Section: Introductionmentioning

confidence: 99%

Methadone toxicity in infants: a report of two fatalities

Mistry

Jeffery

Madira

et al. 2010

Forensic Sci Med Pathol

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Fatalities in infants resulting from methadone toxicity are rare within the United Kingdom. We report two cases of fatality attributed to methadone toxicity in infants aged 3(1/2) and 15 months of age, respectively. One of the two cases was also associated with diazepam ingestion. We discuss the difficulties with the interpretation of paediatric forensic toxicology and review the current literature related to methadone and diazepam toxicity in infants and older children.

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Section: Introductionmentioning

confidence: 99%

Methadone toxicity in infants: a report of two fatalities

Mistry

Jeffery

Madira

et al. 2010

Forensic Sci Med Pathol

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“…The benefits of methadone treatment have been marred by a number of accidental fatal methadone intoxication cases in children (Binchy, Molyneux, & Manning, 1994;Mullin, McAuley, Watts, Crome, & Bloor, 2008), either by unsafe storage procedures (Binchy et al, 1994;Calman, Finsh, Powis, & Strang, 1996) or by parental administration of the drug to an infant for sedation (Couper, Chopra, & Pierre-Louis, 2005;Li, Levine, & Smialek, 2000). Education programmes and public health campaigns may be effective in promoting the dangers of drug intoxication.…”

mentioning

confidence: 99%

Methods of homicide in England and Wales: a comparison by diagnostic group

Rodway

Flynn

Swinson

et al. 2009

Journal of Forensic Psychiatry & Psychology

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Background: International literature has examined the offence characteristics of homicide in the general population, but there has been limited research investigating diagnostic differences between perpetrators who commit homicide by differing methods. Objective: To investigate the methods of homicide by people with different psychiatric diagnoses and to explore the offence characteristics of perpetrators with schizophrenia, in a seven-year (1997)(1998)(1999)(2000)(2001)(2002)(2003) national sample of homicide perpetrators in England and Wales. Results: Of the 3930 homicide perpetrators identified, over a third (36%) used a sharp instrument. The use of firearms was rare. Methods of homicide differed significantly between diagnostic groups. Perpetrators with schizophrenia were more likely to use a sharp instrument and predominantly killed a family member or spouse in the home; a significant majority were mentally ill at the time of the offence. Perpetrators diagnosed with affective disorder were more likely to use strangulation or suffocation. Alcohol dependent perpetrators used hitting or kicking significantly more often, primarily to kill acquaintances. Finally, drug dependent perpetrators were more likely to use non-violent methods, particularly poisoning. Conclusion: Methods of homicide are affected not only by the social and behavioural characteristics of the perpetrator and victim, but also by the perpetrator's psychiatric history and diagnosis.

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“…Une intoxication fatale à la méthadone chez un enfant de 10 mois a donné les résultats suivants [27] : À l'heure actuelle, nous n'avons pu trouver aucune donnée disponible sur la diffusion de la buprénorphine dans l'HV, il serait intéressant en cas d'overdose, de réaliser ce type de dosage dans l'HV. sang [31].…”

Section: Méthadone Et Buprénorphine Dans L'humeur Vitréeunclassified

L’humeur vitrée en toxicologie médico-légale : revue de la littérature et applications

Brunet

Mura

2012

Ann Toxicol Anal

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Fatal methadone intoxication in an infant

Cited by 41 publications

References 5 publications

Methadone toxicity in infants: a report of two fatalities

Methadone toxicity in infants: a report of two fatalities

Methods of homicide in England and Wales: a comparison by diagnostic group

L’humeur vitrée en toxicologie médico-légale : revue de la littérature et applications

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