Faster healing and less pain in skin biopsy sites treated with an occlusive dressing

Nemeth, A. J.

doi:10.1001/archderm.127.11.1679

Cited by 58 publications

(63 citation statements)

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“…Additional benefits of occlusive therapy include pain reduction and a possible improvement in cosmetic outcome of wounds healed by both primary and secondary intentions under occlusion. [31][32][33] In the current study no differences were noted among the groups in reepithelialization rates at days 7 and 14. A prior study in noncontaminated burns found greater reepithelization at day 7 in OCA-treated wounds in comparison with those treated with SSD.…”

Section: Discussioncontrasting

confidence: 63%

Octylcyanoacrylate for the Treatment of Contaminated Partial‐thickness Burns in Swine A Randomized Controlled Experiment

Singer

Mohammad

Tortora

et al. 2000

Academic Emergency Medicine

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Abstract. Objective:To compare infection and reepithelialization rates of contaminated second-degree burns treated with octylcyanoacrylate (OCA), silver sulfadiazine (SSD), polyurethane (PU) film, and dry gauze (control; C) in swine. Methods: Eighty standardized burns were created by applying an aluminum bar preheated to 80ЊC to the backs and flanks of young pigs for 20 seconds. All burns were immediately contaminated with 0

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Section: Discussioncontrasting

confidence: 63%

Octylcyanoacrylate for the Treatment of Contaminated Partial‐thickness Burns in Swine A Randomized Controlled Experiment

Singer

Mohammad

Tortora

et al. 2000

Academic Emergency Medicine

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“…Partial thickness wounds heal primarily by epithelialization that results in restoration of the stratified squamous epithelium, which protects the body from fluid loss, bacterial invasion, electromagnetic radiation, and general trauma [39]. Despite mounting evidence and appreciation of the biological factors of moist environments and their ability to promote rapid infection-free reepithelialization with less pain [12,13,21,23,29,32,40], the advantages of waterimpermeable occlusive dressings on wound healing are often offset by their impracticality particularly when applied to large split thickness donor site areas [13].…”

Section: Introductionmentioning

confidence: 99%

The effect of moist and moist exposed dressings on healing and barrier function restoration of partial thickness wounds

et al. 2003

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Improved healing of full-and partial-thickness cutaneous wounds in wet and moist environments is due primarily to retention of biological fluids over the wound preventing desiccation of denuded dermis or deeper tissues. This also allows faster and unimpeded migration of keratinocytes over the wound surface and enables the naturally occurring cytokines and growth factors to exert their beneficial effect on wound contracture and reepithelialization. Despite all these documented benefits creating and maintaining a sealed moist environment over large surface areas such as large skin graft donor sites or extensive burns is technically difficult if not impossible. The preliminary investigation carried out between 1999 and 2000 studied the healing of a split-thickness skin graft (STSG) following application of moist exposed burn ointment (MEBO). This compound provides a moist environment without the need of an overlying occlusive dressing, and compares favorably with SofraTulle semi-open dressing. Healing of STSG donor sites was then evaluated from January to September 2001 in a prospective study comparing the effect of Tegaderm, a semipermeable membrane occlusive dressing, and MEBO, two different types of moist dressings. Wound healing was evaluated by measuring transepidermal water loss (TEWL), and scar quality was assessed by two independent observers using a visual analogue scale. Faster healing was observed clinically with MEBO application. Physiological healing as determined by TEWL measurements occurred at an extremely significant earlier stage for MEBO, and this was associated with better scar quality demonstrating a positive relationship between function and cosmetic appearance. Moreover, simple ointment application was definitely more practical than application of the occlusive self-adhesive membrane.

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“…It seems that the constant moist environment is most important for pain relief [5]. Occlusive dressing therapy improves the wound healing [6]. …”

Section: Discussionmentioning

confidence: 99%

Treatment and Pain Relief of Ulcerative Hemangiomas with a Polyurethane Film

Oranje

Spek²,

Devillers³

et al. 2000

Dermatology

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Background: Hemangiomas are the most common tumors occurring in young children. The most common complication in the growing phase of hemangioma is ulceration. Aim and Method: We report healing, pain relief and evolutive effects of a polyurethane film in 8 cases with ulcerative hemangiomas. Results: In all 8 infants, prompt pain relief and healing within 1–2 months were observed. An increased regression was also noted within 2–4 months, when the hemangiomas were in the normal proliferative phase. Conclusion: As far as the authors know, there is no explanation for the effectiveness of polyurethane film. Explanations could be the occlusive effects of the film inhibiting proliferation or the decrease in blood flow. As primary initial therapeutic approach in ulcerative hemangiomas, we advocate the application of a polyurethane film. This therapy is painless and suitable for children.

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Faster healing and less pain in skin biopsy sites treated with an occlusive dressing

Cited by 58 publications

References 0 publications

Octylcyanoacrylate for the Treatment of Contaminated Partial‐thickness Burns in Swine A Randomized Controlled Experiment

Octylcyanoacrylate for the Treatment of Contaminated Partial‐thickness Burns in Swine A Randomized Controlled Experiment

The effect of moist and moist exposed dressings on healing and barrier function restoration of partial thickness wounds

Treatment and Pain Relief of Ulcerative Hemangiomas with a Polyurethane Film

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