Familial Retinal Arterial Tortuosity Associated With Tortuosity in Nail Bed Capillaries

Novel COL4A1 mutations associated with HANAC syndrome: A role for the triple helical CB3[IV] domain

“…Arteriolar retinal tortuosity is one of the hallmarks of the vascular involvement in HANAC. Its frequent association with Raynaud phenomena, and the morphological abnormalities of the nail capillaries observed in family F1 further support a generalized vascular defect [Gekeler et al, 2006]. The brain phenotype in HANAC contrasts with the severity of the …”

“…Raynaud phenomena and supraventricular arrhythmia showed intrafamilial variability, but affected at least one patient in each family. Furthermore, abnormal morphology of the nail capillary bed was demonstrated by capillaroscopic examination in family F1 [Gekeler et al, 2006]. The most frequent neurological symptom was migraine.…”

Novel COL4A1 mutations associated with HANAC syndrome: A role for the triple helical CB3[IV] domain

“…Arteriolar retinal tortuosity is one of the hallmarks of the vascular involvement in HANAC. Its frequent association with Raynaud phenomena, and the morphological abnormalities of the nail capillaries observed in family F1 further support a generalized vascular defect [Gekeler et al, 2006]. The brain phenotype in HANAC contrasts with the severity of the …”

“…Raynaud phenomena and supraventricular arrhythmia showed intrafamilial variability, but affected at least one patient in each family. Furthermore, abnormal morphology of the nail capillary bed was demonstrated by capillaroscopic examination in family F1 [Gekeler et al, 2006]. The most frequent neurological symptom was migraine.…”

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“…Raynaud phenomena and supraventricular arrhythmia showed intrafamilial variability, but affected at least one patient in each family. Furthermore, abnormal morphology of the nail capillary bed was demonstrated by capillaroscopic examination in family F1 [Gekeler et al, 2006]. The most frequent neurological symptom was migraine.…”

“… b Nailfold capillaroscopy showing a high degree of tortuosity of capillary loops [Gekeler et al, 2006]. …”

A Case of Carotid Aneurysm in Familial Retinal Arterial Tortuosity

“…Although fRAT is generally considered to be an isolated retinal finding, a few cases with associated systemic vascular anomalies have been reported 2. More recently, a study of nailfold capillaroscopy in patients with fRAT revealed significant tortuosity of the capillaries in all fingers of the patients examined 4. Such evidence suggests that the vascular malformation may not be limited to the retina.…”

Novel COL4A1 mutations associated with HANAC syndrome: A role for the triple helical CB3[IV] domain

“…Arteriolar retinal tortuosity is one of the hallmarks of the vascular involvement in HANAC. Its frequent association with Raynaud phenomena, and the morphological abnormalities of the nail capillaries observed in family F1 further support a generalized vascular defect [Gekeler et al, 2006]. The brain phenotype in HANAC contrasts with the severity of the …”

“…Raynaud phenomena and supraventricular arrhythmia showed intrafamilial variability, but affected at least one patient in each family. Furthermore, abnormal morphology of the nail capillary bed was demonstrated by capillaroscopic examination in family F1 [Gekeler et al, 2006]. The most frequent neurological symptom was migraine.…”

Grafting biodegradable polyesters onto cellulose

“…Raynaud phenomena and supraventricular arrhythmia showed intrafamilial variability, but affected at least one patient in each family. Furthermore, abnormal morphology of the nail capillary bed was demonstrated by capillaroscopic examination in family F1 [Gekeler et al, 2006]. The most frequent neurological symptom was migraine.…”

“… b Nailfold capillaroscopy showing a high degree of tortuosity of capillary loops [Gekeler et al, 2006]. …”

A Case of Carotid Aneurysm in Familial Retinal Arterial Tortuosity

“…Although fRAT is generally considered to be an isolated retinal finding, a few cases with associated systemic vascular anomalies have been reported 2. More recently, a study of nailfold capillaroscopy in patients with fRAT revealed significant tortuosity of the capillaries in all fingers of the patients examined 4. Such evidence suggests that the vascular malformation may not be limited to the retina.…”

Novel COL4A1 mutations associated with HANAC syndrome: A role for the triple helical CB3[IV] domain

“…Arteriolar retinal tortuosity is one of the hallmarks of the vascular involvement in HANAC. Its frequent association with Raynaud phenomena, and the morphological abnormalities of the nail capillaries observed in family F1 further support a generalized vascular defect [Gekeler et al, 2006]. The brain phenotype in HANAC contrasts with the severity of the …”

“…Raynaud phenomena and supraventricular arrhythmia showed intrafamilial variability, but affected at least one patient in each family. Furthermore, abnormal morphology of the nail capillary bed was demonstrated by capillaroscopic examination in family F1 [Gekeler et al, 2006]. The most frequent neurological symptom was migraine.…”

Grafting biodegradable polyesters onto cellulose

“…Raynaud phenomena and supraventricular arrhythmia showed intrafamilial variability, but affected at least one patient in each family. Furthermore, abnormal morphology of the nail capillary bed was demonstrated by capillaroscopic examination in family F1 [Gekeler et al, 2006]. The most frequent neurological symptom was migraine.…”

“… b Nailfold capillaroscopy showing a high degree of tortuosity of capillary loops [Gekeler et al, 2006]. …”

A Case of Carotid Aneurysm in Familial Retinal Arterial Tortuosity

“…Although fRAT is generally considered to be an isolated retinal finding, a few cases with associated systemic vascular anomalies have been reported 2. More recently, a study of nailfold capillaroscopy in patients with fRAT revealed significant tortuosity of the capillaries in all fingers of the patients examined 4. Such evidence suggests that the vascular malformation may not be limited to the retina.…”