Familial benign chronic pemphigus. The role of trauma including contact sensitivity

Familial Benign Chronic Pemphigus Generalized by Pseudomonas Infection

“…Although the trigger for generalization of FBCP is still unclear, various physical and chemical causes have been suspected (6)(7)(8). Local infection has been considered one such trigger.…”

The treatment of pemphigus and pemphigoid*

“…It tends to be worse if the individual is overweight. Friction and infection ofthe skin with staphylococci and with Candida are potent exacerbating factors (Burns et al, 1967;Izumi, Shmunes & Wood, 1971). Systemic flucloxacillin will clear staphylococcal infection and a topical antibacterial and anticandida agent (e.g.…”

Hailey-Hailey disease exacerbated by scabies: the role of dermatoscopy in preventing misdiagnosis

“…Abnormal calcium deposition results in desmosomal separation and acantholysis [2]. The generalized type of the disease is extremely rare and is usually triggered by bacterial or viral infection, arthropod infestation or medication [3][4][5][6][7]. Herein we present the patient with an atypical, generalized exacerbation of the disease, in whom thorough dermoscopic examination led to the identification of the trigger factor -Sarcoptes scabiei superinfection.…”

“…Hailey-Hailey disease is characterized by a chronic and recalcitrant course, however, exacerbations due to infections with pyogenic bacteria or herpes simplex virus, contact allergy, ultraviolet B exposure and mechanical trauma have been mentioned in the literature [3,4]. In such cases, generalized Hailey-Hailey disease may develop, with lesions spreading to non-flexural sites.…”