Factors Related to Subretinal Proliferation in Patients With Primary Rhegmatogenous Retinal Detachment

Abstract

A presumed contaminated intravenous infusion administered in a rural setting was found as a new risk factor for development of endogenous fungal endophthalmitis. These patients were successfully treated with pars plana vitrectomy and oral fluconazole and itraconazole therapy.

Scleral buckling surgery for rhegmatogenous retinal detachment with subretinal proliferation

“…[9][10][11] Despite this prevalence, it has received relatively little attention in the literature. Miura and Ideta 9 reported atrophic retinal breaks, young age, Figure 1 Fundus photography of eyes with retinal detachment associated with subretinal proliferation after successful scleral buckling surgery.…”

“…Subretinal proliferations also known as subretinal strands, subretinal membranes, or subretinal fibrosis are an infrequently discussed subtype of PVR. 9,10 Although subretinal proliferation is classified as grade C PVR, many patients can be treated successfully by scleral buckling surgery. 11,12 The aim of this study was to evaluate the outcome of scleral buckling surgery in patients with RRD associated with subretinal proliferation.…”

Review of Clinical Features, Microbiological Spectrum, and Treatment Outcomes of Endogenous Endophthalmitis over an 8-Year Period

“…Endogenous endophthalmitis is caused by breeching of the blood-ocular barrier by pathogens and is spread by blood-borne route originating from infective foci, for example, endocarditis, liver abscess, urinary tract infection (UTI), and meningitis. Although the infective foci can often be identified, isolated occurrence from iatrogenic source such as dental surgery and contaminated intravenous fluids are also possible [3, 4]. A number of systemic conditions might predispose patients in developing endogenous endophthalmitis, including diabetes mellitus, cardiac diseases, underlying malignancy, immunosuppression, and intravenous drug abuse [5].…”

Reactive Muller Glia as Potential Retinal Progenitors

“…The contractility leads to folds and/or deformations in the retina, causing visual distortions at the very least, and, at worst, can cause retinal detachments [211,212]. Glial membranes/scars are a significant issue in the treatment of visual disorders in humans, occuring in appoximately 15% of retinal detachments [213].…”