“…Until additional data that clarify indications for implantable cardioverter defibrillators in the dialysis population are available, use of leadless pacemakers and defibrillators, or devices with epicardial rather than transvenous leads would be appropriate in those patients suitable for these kinds of devices (23,28). Central vein stenosis could occur in the absence of central vein instrumentation due to extrinsic compression by narrow thoracic inlet, dilated arteries, or benign or malignant growths in adjacent structures (7,20,21). In addition, reports of central vein abnormalities or stenosis in patients on hemodialysis without history of catheters have given rise to the hypothesis that high blood flow rates through fistulas or grafts could directly cause endothelial injury, which in turn leads to neointimal proliferation and stenosis (10,(29)(30)(31).…”