2019
DOI: 10.1371/journal.pone.0222786
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Abstract: BackgroundTB/HIV coinfection is a serious public health issue in Brazil, and patients with coinfection have difficulty adhering to treatments. Directly observed treatment (DOT) has been recommended by the World Health Organization, considering the vulnerability of those affected. The purpose is to investigate the occurrence of DOT and associated factors compared to conventional treatment in Porto Alegre, Brazil.MethodsA retrospective cohort study was carried out with all patients with coinfection from 2009 to … Show more

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Cited by 2 publications
(2 citation statements)
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“…For greater reliability of the study data, information on the total number of coinfected patients and incidence of death was obtained from the National HIV/AIDS Notification System (SINAN-HIV/Aids). In order to link the databases, three personal information items were used: the patient's full name, their mother's name, and their registration number in the public health system [11,25].…”
Section: Study Proceduresmentioning
confidence: 99%
“…For greater reliability of the study data, information on the total number of coinfected patients and incidence of death was obtained from the National HIV/AIDS Notification System (SINAN-HIV/Aids). In order to link the databases, three personal information items were used: the patient's full name, their mother's name, and their registration number in the public health system [11,25].…”
Section: Study Proceduresmentioning
confidence: 99%
“…While DOT in the two‐month intensive phase is associated with a decreased risk of TB relapse , we are unaware of studies assessing the effect of DOT specifically during the longer continuation phase of therapy. DOT is often not provided in low‐ and middle‐income countries (LMIC) as it is less feasible due to limited staffing, increased cost and transportation difficulties compared to higher income countries. The objective of this study was to identify factors associated with unfavourable TB treatment outcomes including mortality, TB treatment failure and recurrence among PLHIV in a large, international cohort collaboration.…”
Section: Introductionmentioning
confidence: 99%