Factors associated with delayed diagnosis and treatment in patients with cancer.

Ökten, İlker; Sezen, Bilge Aktas; Gunaydin, Ulug Mutlu; Koca, Sinan; Ozturk, Turkan; Özder, H. Tahsin; Gümüş, Mahmut

doi:10.1200/jco.2018.36.15_suppl.e22141

Cited by 5 publications

(3 citation statements)

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“…A 2015 Danish study of autoimmune arthritis demonstrated a significant but decreasing time from presentation to diagnosis from 29 to 66 months in the year 2000 to 3 to 4 months by 2011. 44 The discrepancy in diagnostic waiting times extends across all medical specialties even to Oncology, where even with higher cancer screening rates, 45 women have longer diagnostic intervals for several cancers, including, but not limited to: bladder, colorectal, gastric, head and neck, lung, and lymphoma. 46–48 …”

Section: Discussionmentioning

confidence: 99%

Self-Reported Time to Diagnosis and Proportions of Rediagnosis in Female Patients with Chronic Conditions in Australia: A Cross-sectional Survey

Merone

Tsey

Russell

et al. 2022

Women's Health Reports

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Background: The diagnosis of chronic conditions in women is complicated by the historical androcentricity in medical research. Sex and gender gaps in health research may translate to unequal healthcare for women. This cross-sectional survey study aimed to ascertain the median time to diagnosis, proportions of rediagnosis and time to rediagnosis for Australian women with chronic conditions. Methods: An online survey collected anonymous data from voluntary participants. Data were analyzed using Stata14. Cox Proportional Hazards model was used to analyze time to diagnosis and rediagnosis. Logistic regression analysis was used to assess the significance of rediagnosis rates by diagnosis, age at diagnosis, income, employment, state of residence, disability status, and Indigenous status. Results: The median time from first appointment to initial diagnosis was 6 months (range 1 day–50 years) (interquartile range [IQR] 3.74 years). The median time to rediagnosis was 4 years (IQR 9) with a range of 1 day–43 years. Almost half of the women ( n = 161/343, 47%) reported their primary condition being rediagnosed. From the complete responses, 40% were rediagnosed from one organic condition to another organic condition, however, 32% of women originally diagnosed with psychological, medically unexplained syndromes, or chronic pain were later rediagnosed with organic conditions. Conclusion: Median wait times for a diagnosis for women in Australia, when factoring in high rates of rediagnosis and time to rediagnosis, was 4 years. It is important that clinicians are aware of the high rediagnosis rates in female patients with chronic conditions and understand the potential impact of systemic biases on the diagnostic process for women under their care.

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Section: Discussionmentioning

confidence: 99%

Self-Reported Time to Diagnosis and Proportions of Rediagnosis in Female Patients with Chronic Conditions in Australia: A Cross-sectional Survey

Merone

Tsey

Russell

et al. 2022

Women's Health Reports

View full text Add to dashboard Cite

show abstract

“…However, its effectiveness hinges on gathering accurate analytical results in a timely manner. The requirement for specialist equipment, state-of-the-art testing facilities and trained personnel presents a severe bottleneck in current approaches to laboratory testing, which delays the diagnosis with potentially fatal outcomes 7 , 8 . Rapid and minimally invasive point-of-care (PoC) diagnostics ( i.e., medical tests performed near or at the point of patient care), ideally self-manageable, could provide a solution for these problems.…”

Section: Introductionmentioning

confidence: 99%

Microneedle-based devices for point-of-care infectious disease diagnostics

Dixon

Skaria

Lau

et al. 2021

Acta Pharmaceutica Sinica B

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Recent infectious disease outbreaks, such as COVID-19 and Ebola, have highlighted the need for rapid and accurate diagnosis to initiate treatment and curb transmission. Successful diagnostic strategies critically depend on the efficiency of biological sampling and timely analysis. However, current diagnostic techniques are invasive/intrusive and present a severe bottleneck by requiring specialist equipment and trained personnel. Moreover, centralised test facilities are poorly accessible and the requirement to travel may increase disease transmission. Self-administrable, point-of-care (PoC) microneedle diagnostic devices could provide a viable solution to these problems. These miniature needle arrays can detect biomarkers in/from the skin in a minimally invasive manner to provide (near-) real-time diagnosis. Few microneedle devices have been developed specifically for infectious disease diagnosis, though similar technologies are well established in other fields and generally adaptable for infectious disease diagnosis. These include microneedles for biofluid extraction, microneedle sensors and analyte-capturing microneedles, or combinations thereof. Analyte sampling/detection from both blood and dermal interstitial fluid is possible. These technologies are in their early stages of development for infectious disease diagnostics, and there is a vast scope for further development. In this review, we discuss the utility and future outlook of these microneedle technologies in infectious disease diagnosis.

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“…In Brazil, a mortality rate of 20% was reported among 80 patients investigated for visceral leishmaniasis ( Driemeier et al, 2015 ); the cause of death was attributed to delay in diagnosis ( Driemeier et al, 2015 ). In a study to investigate the factors responsible for late diagnosis and treatment of cancer patients, Okten et al (2018) showed that screening rate was higher among women than for men. Okten et al, highlighted patients’ ignorance as being responsible for much (52.2%) of the delay.…”

Section: Introductionmentioning

confidence: 99%

Enablers and hindrances to health promotion and disease prevention practices among healthcare workers in Nelson Mandela Bay Municipality, South Africa

Melariri

Kalinda

Chimbari

2021

Preventive Medicine Reports

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Health promotion (HP) and disease prevention (DP) practices among healthcare workers (HCWs) are key to achieving universal health coverage. This study identified HP and DP enablers and hindrances and compared them at different healthcare levels in Nelson Mandela Bay Municipality, South Africa. An exploratory cross-sectional study using a structured questionnaire was conducted among HCWs (n = 501) from 23 hospitals. Bivariate and multinomial regression were used to analyze the data. The highest number of participants (70.46%; n = 353) were from tertiary hospitals. Thirteen and Eight categories of enablers and hindrances respectively were identified. Of these, eleven enablers and six hindrances of HP and DP were associated with tertiary hospitals; no enabler was identified at both primary and secondary while one hindrance was associated with primary level of health care. Collaboration among disciplines and organizations (Coeff: 2.16, 95% CI: 1.28–3.66) and programme planning (Coeff: 0.375, 95% CI: 0.23–0.62) were the predictors of HP and DP among medical doctors, while staff induction training (Coeff: 0.62, 95% CI: 0.40–0.95) and performance appraisal (Coeff: 1.86, 95% CI: 1.16–2.98) were the enablers among allied health workers. On the other hand, ‘facility promoting treatment more than prevention’ (Coeff: 2.03, 95% CI: 1.30–3.14) and ‘practice guidelines incorporating HP’ (Coeff: 2.79, 95% CI: 1.66–4.70) were the predictors of HP and DP hindrances among medical doctors and allied health workers respectively. Our work indicates the need for an operational strategy designed considering enabling and hindering factors to HP and DP practices for empowering HCWs and enhancing health outcomes.

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Factors associated with delayed diagnosis and treatment in patients with cancer.

Cited by 5 publications

References 0 publications

Self-Reported Time to Diagnosis and Proportions of Rediagnosis in Female Patients with Chronic Conditions in Australia: A Cross-sectional Survey

Self-Reported Time to Diagnosis and Proportions of Rediagnosis in Female Patients with Chronic Conditions in Australia: A Cross-sectional Survey

Microneedle-based devices for point-of-care infectious disease diagnostics

Enablers and hindrances to health promotion and disease prevention practices among healthcare workers in Nelson Mandela Bay Municipality, South Africa

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