Factors associated with atherogenic dyslipidemia among hypertensive patients at southern Ethiopia

Hirigo, Agete Tadewos; Geleta, Eshetu Nigussie

doi:10.5897/ijmms2018.1357

Cited by 5 publications

(19 citation statements)

References 29 publications

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“…This could be explained by as waist circumference increases energy might be stored in different forms of lipids. Contrary to the findings in many previous studies [ 9 , 15 , 16 , 18 , 28 ], BMI was not significantly associated with dyslipidemia in this study. This could be explained by the evidence that BMI was pointed as a poor indicator of obesity or body fatness in previous studies [ 34 ].…”

Section: Discussioncontrasting

confidence: 99%

“…The prevalence of elevated LDL-C in this study, 21.5% is comparable with the study findings reported in Hawassa, southern Ethiopia, 21% [ 16 ], Africa, 21.4% [ 4 ], India, 23% [ 22 ], and Venezuela, 23.3% [ 27 ]. However, it is higher than the study findings reported in China, 8.3% [ 1 ], Ethiopia, 14.1% [ 9 ], and India, 15.8% [ 29 ].…”

Section: Discussionsupporting

confidence: 89%

“…The reason for the high prevalence in this study might be attributed to differences in sample sizes, study setting, study population, socio-economic status, and lifestyle of the study participants [ 23 ]. In contrast, the prevalence is lower than the findings reported in Iran, 83.4% [ 26 ], and Hawassa, southern Ethiopia, 90.8% [ 16 ]. The presence of co-morbidity might be the main reason for the higher prevalence in the study from Southern Ethiopia [ 20 ], as it was conducted among hypertensive patients.…”

Section: Discussioncontrasting

confidence: 61%

“…The prevalence of elevated triglyceride in this study, 33.4% is higher than the findings reported in Nigeria, 5% [ 25 ], Africa, 17% [ 4 ], Ethiopia, 21% [ 9 ], China, 22.5% [ 1 ], and India, 27% [ 22 ]. However, higher prevalence were reported in studies conducted in Venezuela, 39.7% [ 27 ], Mekelle, 40.2% [ 18 ], Saudi Arabia, 44% [ 7 ], and Hawassa, southern Ethiopia, 62.2% [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of elevated total cholesterol in this study, 25.4% is almost consistent with the study findings reported in Venezuela, 22.2% [ 27 ], Nigeria, 23% [ 25 ], Durame, southern Ethiopia, 23.7% [ 15 ], and Africa, 25.5% [ 4 ]. Whereas, higher prevalence of elevated total cholesterol was reported in studies conducted in different parts of Ethiopia; Mekelle, 30.8% [ 18 ], Eastern Ethiopia, 33.7%, Hawassa, southern Ethiopia, 38.7% [ 16 ], and Togo, 64% [ 5 ]. In contrast, lower prevalence were reported in studies from Ethiopia, 5.2% [ 9 ], India, 15.3% [ 22 ], and Zambia, 15.8% [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

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Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

Angassa

Solomon

Seid

2022

BMC Cardiovasc Disord

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Background Dyslipidemia is a highly prevalent and modifiable risk factor for atherosclerotic cardiovascular diseases. Though the problem is significant in Ethiopia, available data in this regard is very poor among alcoholic beverage industrial workers. This study aimed to assess factors associated with dyslipidemia and its prevalence among Awash wine factory employees in Addis Ababa, Ethiopia. Methods A cross-sectional study was conducted among 335 randomly selected employees of Awash wine factory, Addis Ababa, Ethiopia from January to February 2021. Data was collected by a face-to-face interview technique using the WHO STEPwise approach. Data were entered and analyzed using Epi Info 7 and SPSS version 26, respectively. Both bivariable and multivariable logistic regression analyses were performed to identify factors associated with dyslipidemia. All statistical tests were declared significant at p-value < 0.05. Results The overall prevalence of dyslipidemia was 67.8% (95% CI 62.5–72.7%). Elevated total cholesterol, elevated triglycerides, reduced high-density lipoprotein, and elevated low-density lipoprotein was found in 25.4%, 33.4%, 50.7%, and 21.5% of participants, respectively. Dyslipidemia was significantly associated with age group 30–39 years (AOR = 2.51; 95% CI 1.16–5.44, p = 0.019), ≥ 40 years (AOR = 6.45; 95% CI 2.01–20.71, p = 0.002), current alcohol consumption (AOR = 3.37; 95% CI 1.70–6.66, p < 0.001), eating vegetables < 2 days per week (AOR = 2.89; 95% CI 1.54–5.43, p = 0.001), sitting duration of > 4 h per day (AOR = 1.96; 95% CI 1.03–3.74, p = 0.041), and raised waist circumference (AOR = 4.56; 95% CI 2.07–10.08, p < 0.001). Conclusions High prevalence of dyslipidemia was found among Awash wine factory employees in Addis Ababa. Periodic screening of high-risk groups along with effective health promotion and education which encourages a healthy lifestyle is essential.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 89%

Section: Discussioncontrasting

confidence: 61%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

Angassa

Solomon

Seid

2022

BMC Cardiovasc Disord

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Prevalence and Associated Factors of Dyslipidemia Among Psychiatric Patients on Antipsychotic Treatment at Hawassa University Comprehensive Specialized Hospital

Hirigo

Teshome

Gitore

et al. 2021

Nutr Metab Insights

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Background: Dyslipidemia is one of the adverse metabolic outcomes associated with psychotropic medications and the nature of the mental illness itself. Therefore, this study aimed to assess magnitude of dyslipidemia and associated factors among patients with severe mental illness on antipsychotic treatments. Methods: A cross-sectional study was conducted among 245 patients with severe mental illness in Hawassa University Comprehensive Specialized Hospital, Sidama Regional state, Southern Ethiopia. Socio-demographic and other important data were collected using a structured questionnaire through a systematic random sampling technique. Individual dyslipidemia was characterized by the National Cholesterol Education Program Adult Treatment Panel-III (NCEP ATP-III) guideline. Results: Mean total cholesterol (TC) was significantly higher in males when compared to females (162.2 mg/dl vs 121 mg/dl, P = .023). While, mean LDL-cholesterol was significantly higher in females when compared to males (100.9 mg/dl vs 93.6 mg/dl, P = .028). Overall 58.4% (95% CI: 52.2-64.8) of participants had at least 1 dyslipidemia. The prevalence of TC ⩾200 mg/dl, HDL-cholesterol <40 mg/dl, triglyceride (TG) and LDL-cholesterol were 61 (24.9%), 75 (30.6%), 66 (26.9%), and 47 (19.2%), respectively. Female sex and smoking were significantly and positively associated with LDL-c dyslipidemia, the aOR (95% CI) were 2.1 (1.0-4.2) for female sex and 3.4 (1.1-10.5) for smoking. Also, Age >40 years was significantly associated with TC dyslipidemia, the aOR (95% CI) was 2.0 (1.1-3.7). Conclusion: More than half of psychiatric patients are at risk of developing cardiovascular and other related health problems. Therefore, periodic screening of lipid profiles during healthcare follow-up is mandatory to limit risks of cardiovascular-related comorbidities among patients with severe mental illness.

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Atherogenic dyslipidemia and associated risk factors among hypertensive patients of five health facilities in Northeast Ethiopia

et al. 2023

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Background One of the major risk factors for cardiovascular disease is atherogenic dyslipidemia. There was, however, little information available in Ethiopia. Therefore, the purpose of this study was to estimate the prevalence of atherogenic dyslipidemia and related risk factors in Northeast Ethiopian hypertension patients. Materials and methods A systematic random sampling technique was used to perform a cross-sectional study at an institution with 384 chosen participants. A structured questionnaire was used to collect the socio-demographic, anthropometric, lifestyle, and clinical characteristics of the respondents. Student’s t-test, Mann-Whitney test, and Pearson’s Chi-square test were employed to compare groups based on the type of data. Furthermore, Bivariate and multivariable logistic regression analyses were performed to identify factors independently associated with dyslipidemia. Crude and adjusted odds ratios and their corresponding 95% Confidence Intervals (CI) were computed. In all cases, statistical significance was declared at p <0.05. Results The majority (93.2%; 95%CI: 90.6–95.6) of patients had at least one atherogenic dyslipidemia. The prevalence of elevated total cholesterol (TC), elevated triglyceride (TG), raised low-density lipoprotein cholesterol (LDL-c), and reduced high-density lipoprotein cholesterol (HDL-c) were 47.7%, 50.3%, 44.3%, and 59.6%, respectively. Being≥ 40 years were at higher risk for having elevated levels of TC (AOR: 3.22, 95% CI: 2.40–4.32), TG (AOR: 2.30, 95% CI: 1.61–3.79), and LDL-c (AOR: 4.68, 95% CI: 2.0–10.95) than those who were below 40years. Obese participants were more likely to have high concentrations of TC (AOR: 2.57, 95%CI: 2.10–3.22), LDL-c (AOR: 3.13, 95% CI: 1.97–5.10), HDL-c (AOR: 2.71, 95% CI: 1.77–4.58), and TG (AOR: 2.23, 95%CI: 1.79–4.16). Conclusion This study revealed that a high prevalence of atherogenic dyslipidemia. Thus, to prevent atherogenic dyslipidemia, it is crucial to create routine blood lipid testing programs and carry out suitable intervention programs focused on risk factor reduction.

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Factors associated with atherogenic dyslipidemia among hypertensive patients at southern Ethiopia

Cited by 5 publications

References 29 publications

Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

Factors associated with dyslipidemia and its prevalence among Awash wine factory employees, Addis Ababa, Ethiopia: a cross-sectional study

Prevalence and Associated Factors of Dyslipidemia Among Psychiatric Patients on Antipsychotic Treatment at Hawassa University Comprehensive Specialized Hospital

Atherogenic dyslipidemia and associated risk factors among hypertensive patients of five health facilities in Northeast Ethiopia

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