Factors affecting perioperative mortality in tetralogy of Fallot

Abstract

Poor preoperative oxygenation, presence of coronary anomaly, complete AV block in the early postoperative period, high RV pressure and requirement of ECMO appear to be the most significant factors that affect early mortality in the surgical treatment of TOF. Appropriate preoperative assessment, correct surgical strategies and attentive intensive care monitoring are required in order to reduce mortality.

Factors associated with perioperative mortality in children and adolescents operated for tetralogy of Fallot: A sub‐Saharan experience

“…In our series, 8 of 62 (12.9%) patients died during the perioperative period. This is higher than reported in many studies from the developed world, which report on younger patient populations and have more advanced perioperative facilities. As a surgical intervention for CHDs including TOF is not readily available in most sub‐Saharan countries, few studies exist against which we can compare our results.…”

The impact of pulmonary valve-sparing techniques on postoperative early and midterm results in tetralogy of Fallot repair

“…While there was no significant difference in terms of mortality in the patients with monocusp insertion, there was a significant decrease in morbidity. In a study by Saygi et al [9] of 122 patients who had undergone total correction operation, it was reported that nine patients (7.3%) were lost and perioperative early term mortality determinants were poor preoperative oxygenation, presence of coronary anomaly, development of block in the early postoperative period, high right ventricular pressure, and need for postoperative ECMO support. Right ventricle/left ventricle peak systolic pressure rate was an important criteria in the postoperative evaluation of presence of RVOT stenosis.…”

Effect of Concomitant Birth Defects and Genetic Anomalies on Infant Mortality in Tetralogy of Fallot

“…This is consistent with our finding that infant nonsurvivors were significantly more likely to have pulmonary atresia but not pulmonary stenosis. Coronary anomalies have also been associated with worse early outcomes, a finding possibly related to the complexity of the required surgery (Saygi et al, ). In the current study, we did not find coronary anomalies to significantly affect 1‐year mortality.…”

“…Tetralogy of Fallot (TOF) is the most common type of complex CHD, affecting approximately 4 in 10,000 newborns in the United States each year (Egbe et al, 2014;Mai et al, 2015). Surgical correction is the only definitive treatment for TOF (Saygi et al, 2015). Left surgically unrepaired, TOF has a 66% survival rate at 1 year; with surgery, greater than 95% of infants can expect to survive into adulthood (Bertranou et al, 1978;Barron, 2013).…”