Factors affecting allatostatin release in a cockroach (Diploptera punctata): Nerve section, juvenile hormone analog and ovary

Stay, Barbara; Bachmann, Jane A.S.; Stoltzman, Carrie A.; Fairbairn, Steve; Yu, C.G.; Tobe, Stephen S.

doi:10.1016/0022-1910(94)90154-6

Cited by 41 publications

(14 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The brain is an important source of allatostatins and allatotropins in other insects (e.g., Woodhead et al, 1989;Donly et al, 1993;Stay et al, 1994), and it is likely that similar mechanisms operate in honey bees, but this has not yet been demonstrated.…”

Section: Jh and Age-related Division Of Labor: Current Issuesmentioning

confidence: 96%

Juvenile hormone in adult eusocial hymenoptera: Gonadotropin and behavioral pacemaker

Robinson

Vargo

1997

Arch. Insect Biochem. Physiol.

289

191

View full text Add to dashboard Cite

Section: Jh and Age-related Division Of Labor: Current Issuesmentioning

confidence: 96%

Juvenile hormone in adult eusocial hymenoptera: Gonadotropin and behavioral pacemaker

Robinson

Vargo

1997

Arch. Insect Biochem. Physiol.

289

191

View full text Add to dashboard Cite

“…First, although great progress has been made in understanding regulation of corpora allata production of JH during the reproductive cycle of adult female insects, little is known about the regulation of corpora allata activity in honey bees. The brain is an important source of allatostatins (peptides that inhibit JH synthesis) and allatotropins (peptides that stimulate JH synthesis) in cockroaches [Woodhead et al, 1989;Donly et al, 1993;Stay et al, 1994], and it is likely that similar mechanisms operate in honey bees. Changes in JH production that result from changes in the physical or social environment of honey bees are likely to be medi ated through these as yet uncharacterized brain path ways.…”

Section: Regulation Of Juvenile Hormone III Production and Receptors mentioning

confidence: 99%

Juvenile Hormone, Behavioral Maturation, and Brain Structure in the Honey Bee

Fahrbach

Robinson²

1996

Dev Neurosci

118

View full text Add to dashboard Cite

Juvenile hormone regulates metamorphosis in insects, and its effects on the nervous system during the larval-pupal transition have been studied primarily in the hawk moth, Manduca sexta. The effects of juvenile hormone on the nervous system of adult insects have been little studied. Elucidating the role of juvenile hormone during behavioral development in adult honey bees provides an opportunity to study hormone regulation of nervous system structure and function in an insect with a rich behavioral repertoire and social life. A worker honey bee typically lives 30–60 days. During this time, she performs a sequence of different tasks that sustain the colony. A striking behavioral transition typically occurs at about 3 weeks of age. At this time, worker bees stop performing within-hive tasks such as rearing brood and building comb and begin to forage outside the hive. This behavioral development is accompanied by a marked increase in the production of juvenile hormone. The mushroom bodies of the protocerebrum, the region of the insect brain most often associated with learning and memory, also undergo an internal reorganization during behavioral development. High titers of juvenile hormone and an increased volume of neuropil associated with the mushroom bodies are characteristic of the forager. Importantly, the time of the behavioral transition to foraging is not fixed. Individual bees can respond to changing colony or environmental conditions by accelerating or delaying the switch from within-hive tasks to foraging. For example, in the absence of older workers, some bees will undergo precocious development and may forage as early as 4 days of age. These workers also experience a precocious rise in juvenile hormone and an earlier reorganization of the mushroom bodies. Our current studies investigate the roles played by juvenile hormone and experience in shaping the mushroom bodies of the adult honey bee, and the relationship of these changes to the bee's ability to forage successfully. It is proposed that juvenile hormone may mediate neural plasticity in the brains of adult honey bees to support the demanding cognitive task of foraging.

show abstract

“…Although the function of hemocyte allatostatin has not been addressed in this study, we may speculate that it could contribute to one or more of the demonstrated or proposed functions for allatostatins in cockroaches, i.e., modulation of activity of corpora allata, muscle and neurons (Stay et al 1994b). Experiments have demonstrated that allatostatins can limit juvenile hormone production and titer by a humoral route (Woodhead et al 1993;Stay et al 1994a;Weaver et al 1994) and inhibit visceral muscle contraction (Lange et al 1993). However, because neurosecretions including allatostatins are rapidly degraded in the hemolymph (Stay et al 1994b), it is more likely that allatostatin-containing hemocytes are acting locally.…”

Section: Discussionmentioning

confidence: 92%

Allatostatin in hemocytes of the cockroach Diploptera punctata

Skinner

Fairbairn

Woodhead

et al. 1997

Cell and Tissue Research

View full text Add to dashboard Cite

Allatostatins are neuropeptides that inhibit the production, by the corpora allata, of a major insect hormone, juvenile hormone. These peptides are produced by cells of the brain and ganglia as well as by midgut endocrine cells. Transport from these sites may contribute to the allatostatin content in the hemolymph (insect blood). Using a monoclonal antibody against Diploptera punctata allatostatin I (A-P-S-G-A-Q-R-L-Y-G-F-G-L-NH2) and in situ hybridization with a digoxigenin-labeled cRNA probe generated from a portion of the allatostatin gene, it is demonstrated that allatostatin is present in and synthesized by granular hemocytes of D. punctata. About 5% of the hemocytes react with anti-allatostatin antibody and a similar number hybridize with a cRNA probe that detects allatostatin-specific mRNA. Electron micrographs showed that allatostatin-immunoreactive material occurs in membrane-bound, uniformly dense granules that frequently fill fusiform-shaped cells. Allatostatin in cell and plasma fractions of hemolymph quantified by enzyme-linked immunosorbent assay and by bioassay for inhibition of juvenile hormone synthesis in vitro indicated that about equal quantities (0.1-0.2 fmol/microl) are present in cell and plasma fractions. The production of allatostatin by hemocytes suggests that allatostatins may function as regulatory peptides in hemolymph activities in addition to their other known functions.

show abstract

Factors affecting allatostatin release in a cockroach (Diploptera punctata): Nerve section, juvenile hormone analog and ovary

Cited by 41 publications

References 26 publications

Juvenile hormone in adult eusocial hymenoptera: Gonadotropin and behavioral pacemaker

Juvenile hormone in adult eusocial hymenoptera: Gonadotropin and behavioral pacemaker

Juvenile Hormone, Behavioral Maturation, and Brain Structure in the Honey Bee

Allatostatin in hemocytes of the cockroach Diploptera punctata

Contact Info

Product

Resources

About