Facilitated bioaccumulation of perfluorooctanesulfonate in zebrafish by nano-TiO2 in two crystalline phases

Qiang, Liwen; Xiao-mei, Shi; Pan, Xiaoyu; Zhu, Lingyan; Chen, Meng; Yan, Han

doi:10.1016/j.envpol.2015.08.032

Cited by 25 publications

(8 citation statements)

References 44 publications

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“…In addition, the bioavailability and toxicity of some toxic substances, such as decabromobiphenyl ether (BDE-209), perfluorooctanesulfonate (PFOS), and pentachlorophenol (PCP), can be increased by using TiO 2 NPs as carriers. When these substances interact with TiO 2 NPs, the toxicity to zebrafish shall greatly increase [18,20,21,22].…”

Section: Discussionmentioning

confidence: 99%

Toxic Effects of TiO2 NPs on Zebrafish

Tang

Zhang

Zhu

2019

IJERPH

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Titanium dioxide nanoparticles (TiO2 NPs) have become a widely used nanomaterial due to the photocatalytic activity and absorption of ultraviolet light of specific wavelengths. This study investigated the toxic effects of rutile TiO2 NPs on zebrafish by examining its embryos and adults. In the embryo acute toxicity test, exposure to 100 mg/L TiO2 NPs didn’t affect the hatching rate of zebrafish embryos, and there was no sign of deformity. In the adult toxicity test, the effects of TiO2 NPs on oxidative damage in liver, intestine and gill tissue were studied. Enzyme linked immunosorbent assay (ELISA) and fluorescence-based quantitative real-time reverse transcription PCR (qRT-PCR) were used to detect the three antioxidant enzymes: superoxide dismutase (SOD), catalase (CAT) and glutathione S transferase (GSTs) in the above mentioned zebrafish organs at protein and gene levels. The results showed that long-term exposure to TiO2 NPs can cause oxidative damage to organisms; and compared with the control group, the activity of the three kinds of enzyme declined somewhat at the protein level. In addition, long-term exposure to TiO2 NPs could cause high expression of CAT, SOD and GSTs in three organs of adult zebrafish in order to counter the adverse reaction. The effects of long-term exposure to TiO2 NPs to adult zebrafish were more obvious in the liver and gill.

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Section: Discussionmentioning

confidence: 99%

Toxic Effects of TiO2 NPs on Zebrafish

Tang

Zhang

Zhu

2019

IJERPH

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“…The bioaccumulation of perfluorooctane sulfonate (a persistent organic pollutant) in zebrafish was facilitated by nano-TiO 2 anatase/rutile mixture exposure. [150] However, during co-exposures to strong prooxidants such as paraquat, dioxins, or toxic metals, nano-TiO 2 might exert protective effects in fish. Thus, in a common carp, exposure to nano-TiO 2 anatase/rutile mixture mitigated the toxic effects of paraquat under the UV light.…”

Section: Aquatic Vertebratesmentioning

confidence: 99%

Rethinking Nano‐TiO₂ Safety: Overview of Toxic Effects in Humans and Aquatic Animals

Luo

Xie

et al. 2020

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122

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Titanium dioxide nanoparticles (nano‐TiO2) are widely used in consumer products, raising environmental and health concerns. An overview of the toxic effects of nano‐TiO2 on human and environmental health is provided. A meta‐analysis is conducted to analyze the toxicity of nano‐TiO2 to the liver, circulatory system, and DNA in humans. To assess the environmental impacts of nano‐TiO2, aquatic environments that receive high nano‐TiO2 inputs are focused on, and the toxicity of nano‐TiO2 to aquatic organisms is discussed with regard to the present and predicted environmental concentrations. Genotoxicity, damage to membranes, inflammation and oxidative stress emerge as the main mechanisms of nano‐TiO2 toxicity. Furthermore, nano‐TiO2 can bind with free radicals and signal molecules, and interfere with the biochemical reactions on plasmalemma. At the higher organizational level, nano‐TiO2 toxicity is manifested as the negative effects on fitness‐related organismal traits including feeding, reproduction and immunity in aquatic organisms. Bibliometric analysis reveals two major research hot spots including the molecular mechanisms of toxicity of nano‐TiO2 and the combined effects of nano‐TiO2 and other environmental factors such as light and pH. The possible measures to reduce the harmful effects of nano‐TiO2 on humans and non‐target organisms has emerged as an underexplored topic requiring further investigation.

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“…The presence of coating (PVP) and of different NPs had little effect on pesticide bioavailability under current growth conditions. Although there is a growing literature on the interactions of engineered nanomaterials with coexisting organic and inorganic contaminants , little information is available on terrestrial systems involving pesticides and biota, specifically soil invertebrates. Although results from the limited number of studies available with earthworms and plant species are mixed, the general trends seem to support the present findings of reduced pesticide bioavailability on NP exposure.…”

Section: Resultsmentioning

confidence: 99%

Nanoparticle silver coexposure reduces the accumulation of weathered persistent pesticides by earthworms

Mukherjee

Hawthorne

White

et al. 2017

Enviro Toxic and Chemistry

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Although the use of engineered nanomaterials continues to increase, how these materials interact with coexisting contaminants in the environment is largely unknown. The effect of silver (Ag) in bulk, ionic, and nanoparticle (NP; bare and polyvinyl pyrrolidone-coated) forms at 3 concentrations (0 mg/kg, 500 mg/kg, 1000 mg/kg, 2000 mg/kg; ion at 69 mg/kg, 138 mg/kg, 276 mg/kg) on the accumulation of field-weathered chlordane and dichlorodiphenyldichloroethylene + metabolites (DDX) by Eisenia fetida (earthworm) was investigated. Earthworm biomass and survival were unaffected by treatment. At the 500 mg/kg and 1000 mg/kg exposure levels, NP-exposed earthworms contained significantly greater Ag (194-245%) than did the bulk exposed organisms; NP size or coating had no impact on element content. Generally, exposure to Ag of any type or at any concentration significantly reduced pesticide accumulation, although reductions for DDX (35.1%; 8.9-47.0%) were more modest than those for chlordane (79.0%; 17.4-92.9%). For DDX, the reduction in pesticide accumulation was not significantly affected by Ag type or concentration. For chlordane, the 3 NP exposures suppressed chlordane accumulation significantly more than did bulk exposure; earthworms exposed to bulk Ag contained 1170 ng/g chlordane, but levels in the NP-exposed earthworms were 279 ng/g. At the 500 mg/kg exposure, the smallest coated NPs exerted the greatest suppression in chlordane accumulation; at the 2 higher concentrations, chlordane uptake was unaffected by NP size or coating. The findings show that in exposed earthworms Ag particle size does significantly impact accumulation of the element itself, as well as that of coexisting weathered pesticides. The implications of these findings with regard to NP exposure and risk are unknown but are the topic of current investigation. Environ Toxicol Chem 2017;36:1864-1871. © 2016 SETAC.

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Facilitated bioaccumulation of perfluorooctanesulfonate in zebrafish by nano-TiO2 in two crystalline phases

Cited by 25 publications

References 44 publications

Toxic Effects of TiO2 NPs on Zebrafish

Toxic Effects of TiO2 NPs on Zebrafish

Rethinking Nano‐TiO₂ Safety: Overview of Toxic Effects in Humans and Aquatic Animals

Nanoparticle silver coexposure reduces the accumulation of weathered persistent pesticides by earthworms

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Facilitated bioaccumulation of perfluorooctanesulfonate in zebrafish by nano-TiO2 in two crystalline phases

Cited by 25 publications

References 44 publications

Toxic Effects of TiO2 NPs on Zebrafish

Toxic Effects of TiO2 NPs on Zebrafish

Rethinking Nano‐TiO2 Safety: Overview of Toxic Effects in Humans and Aquatic Animals

Nanoparticle silver coexposure reduces the accumulation of weathered persistent pesticides by earthworms

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Product

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Rethinking Nano‐TiO₂ Safety: Overview of Toxic Effects in Humans and Aquatic Animals