Facial transplantation: historical developments and future directions

Garrett, G.; Beegun, Issa; D’Souza, Alwyn

doi:10.1017/s0022215114003478

Cited by 19 publications

(18 citation statements)

References 46 publications

(58 reference statements)

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“…3). In all 148 articles included, nonmaleficence was the most frequent ethical principle addressed (117/148, 79.1%), 1–3,7,10–121 followed by beneficence (116/148, 78.3%), 1–3,5,7,10,13–24,26–29,32–42,44,46,48,49,51–56,58,60,61,63–66,69–84,86,87,89–93,95–137 justice (103/148, 69.6%), 2,3,5,7,11,14,17–22,24–28,30–32,34,35,38,39,41–44,46,48,49,51,52,54,55,57,58,60–64,66–73,75–77,79,82–85,87–92,94,95,97–102,104,105,107–112,114,117,119–121,123,125,129–131,135,138–147 and autonomy (86/148, 58.1%). 1–3,5,7…”

Section: Resultsmentioning

confidence: 99%

The Ethics of Facial Allotransplantation: A Systematic Review

Liu

Langsdon

Holloway

et al. 2019

Plastic and Reconstructive Surgery - Global Open

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Section: Resultsmentioning

confidence: 99%

The Ethics of Facial Allotransplantation: A Systematic Review

Liu

Langsdon

Holloway

et al. 2019

Plastic and Reconstructive Surgery - Global Open

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“…The patient has not presented with any clinical or pathologic signs indicative of chronic vascular rejection and has a functioning graft. Notably, none of the numerous reports of acute rejection in FAT recipients has been shown to correlate with HLA mismatch . Nonetheless, Chandraker's single case report of manageable ABMR rejection does not constitute sufficient evidence to reduce the current cautionary approach in sensitized FAT recipients.…”

Section: Patient Selection/inclusion–exclusion Criteriamentioning

confidence: 99%

Face transplantation-current status and future developments

et al. 2018

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More than thirty-five facial allograft transplantations (FAT) have been reported worldwide since the pioneering case performed in France in the year 2005. FAT has received tremendous interest by the medical field and the general public while gaining strong support from multiple disciplines as a solution for reconstructing complex facial defects not amenable/responsive to conventional methods. FAT has expanded the frontiers of reconstructive microsurgery, immunology and transplantation, and established its place in the cross section of multiple disciplines. The procedure introduces complex scientific, ethical, and societal issues. Patients and physicians are called to deal with a variety of-sometimes everlasting-challenges, such as immunosuppression management and psychosocial hurdles. This review reflects on the surgical and scientific advancements in FAT and milestones reached in the last 12 years. It aims to encourage active discussion regarding the current practices and techniques used in FAT and suggest future directions that may allow transitioning into the next phase of FAT, which we describe as safe, reliable, and accessible standard operation for selected patients.

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“…Table 4 shows Compilation of published face transplant cases, most recent outcomes and complications. [21][22][23][24][25][26][27][28][29]…”

Section: Pain Reduction and Discomfortmentioning

confidence: 99%

Face transplant: A revolutionary approach and role of dentist

Nandkeoliar¹,

Deb²

2018

JCRI

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Face transplant forms a part of vascularized composite tissue allotransplantation (transfer of organs or tissue from one individual to another), which is the basis of modern microsurgery and reconstructive plastic surgery. A face transplant is a medical procedure to replace all or part of a person's face using tissue from a cadaver. Face transplantation can include skin from the face, neck and/or scalp, lips and tongue, muscles used for facial movement and expression, and nerves to animate as well as to provide sensation. Supportive bony structures can also be included. Oral surgeons play a major role in alignment of teeth, reconstruction of midface, maxilla, mandible including teeth, and tongue. It gives better esthetics and functional results including increase in the opening of mouth, chewing, and breathing. The new computer-assisted planning and execution system aims to make it less likely to misalign the new set of bones, jaws, and prevent other reconstructive abnormalities. In spite of risks and rejection, face transplant gives a better appearance, i.e., gives a new life to the patient and improves his social status and lifestyle.

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Facial transplantation: historical developments and future directions

Cited by 19 publications

References 46 publications

The Ethics of Facial Allotransplantation: A Systematic Review

The Ethics of Facial Allotransplantation: A Systematic Review

Face transplantation-current status and future developments

Face transplant: A revolutionary approach and role of dentist

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