“…Various interferometric techniques have been adapted to microfluidic systems to precisely measure the average refractive index of a single (as low as~μm 3 ) point in space, down to 10 −4 to 10 −7 RIU, including a Mach-Zehnder interferometer, 23 a back scattering interferometer, 24 a Young interferometer, 25 and Fabry-Perot interferometers. [26][27][28] To our knowledge, only one refractometry method, consisting of a Fabry-Perot interferometer with a monochromator, is able to resolve spatial refractive index profiles in a fluidic system. 29 This technique is optimized for measurements in nanofluidic channels and not immediately applicable to measuring evolving concentration profiles in microfluidic channels.…”