Fabrication of surface enhanced Raman spectroscopy substrates on solid supports

Facile Bacterial Cellulose Nanofibrillation for the Development of a Plasmonic Paper Sensor

“…In R6G series screening, a typical Raman band at 1576 cm -1 attributed to strong aromatic carbon bond had shown the most conspicuous peak and was plotted in calibration curves where 10 different point positions were taken to ascertain the uniform distribution of the AgNPs on both plasmonic BC and NBC papersheet, as well as the low deviated signals presented in Figure 6c and d. With the dynamic range of 10 -12 to 10 -6 M of R6G, the NBC sheet with its high SERS hotspots has exhibited more than 50% higher sensitivity than the BC sheet and with the limitation of detection (LoD) of 92 fM as calculated based on the lowest concentration of the R6G producing the alteration in the Raman intensity signal equal to the three times the average background signals without the presence of R6G. The intensity of the strongest R6G Raman peak at 1576 cm -1 was later applied in the calculation of SERS enhancement factor (EFSERS) with the formula below: EFSERS = ISERS/NSERS IR6G norm/NR6G norm where ISERS and IR6Gnorm refer to the SERS and normal Raman intensities of R6G molecules, whilst, NSERS and NR6Gnorm are the number in average of R6G molecules in the scattering volume (V) giving out both normal and Raman intensities [40], [43]. In Figure 7a and b, effective SERS hotspots from AgNPs entrapment within the cellulose fibrils was apparent in comparison with the as prepared BC and NBC papersheets with optimum spike in the plasmonic NBC which reflects favourable effects of HPH for molecular capture.…”

Sandwich‐based surface‐enhanced Raman scattering probes for detection and quantification of malaria

“…Figure S1 shows SEM micrograph and EDS of the lab‐chip SERS substrate. Their fabrication is detailed in reference [19]. Ag‐MBA conjugate and Ag‐MBA detection hybrid SERS spectra are shown in Figure 1.…”

“…The metal colloids, Ag and Au, were synthesized as outlined in our previous work [19]. Metal precursors (AgNO 3 /HAuCl 4 ·3H 2 O) were reduced using C 6 H 5 Na 3 O 7 ·2H 2 O.…”

“…SERS substrates detailed in our previous work [19] were used to immobilize the malaria mAbs. The substrates were self‐assembled with 4 mM of HS‐PEG‐COOH overnight in a centrifuge tube and backfilled with N 2 .…”

A P/N type silicon semiconductor loaded with silver nanoparticles used as a SERS substrate to selectively drive the coupling reaction induced by surface plasmons

“…Recent research has focused on semiconductor-metal nanoparticle systems, such as Si/GaN-Au/Ag nanoparticles. 28,29 In this system, the substrate morphology and synthesis process can affect the detection performance of SERS. 18,30,31 Therefore, this paper provides a method for preparing SERS composite substrates with strong and reusable silicon semiconductorsilver nanoparticles synthesized by the self-assembly method, and analyses the regulation process of the electron (hole) caused by the optical drive charge transfer.…”