Abstract:Incorporation of the reducible disulfide links into delivery systems has been repeatedly highlighted to realize, elegantly, the tradeoff between extracellular stability and intracellular high therapeutic efficacy. Of all the reported introducing strategies, esterification, seemingly the most extensively‐adopted one, suffers from relatively low yield, especially for the esterification coupling between two macromolecules, due to the low condensation efficiency. To improve the coupling efficiency, Cu(I)‐catalyzed… Show more
Stimuli-responsive polymeric micelles via click chemistry are divided into six major sections (temperature, light, ultrasound, pH, enzymes, and redox).
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