Fabrication of 3D chitosan–hydroxyapatite scaffolds using a robotic dispensing system

Ang, Thiam Hong; Sultana, Fariha; Hutmacher, Dietmar W.; Wong, Yoke San; Fuh, Jerry Ying Hsi; Mo, Xiumei; Loh, Han Tong; Burdet, Etienne; Teoh, Swee‐Hin

doi:10.1016/s0928-4931(02)00010-3

Cited by 248 publications

(137 citation statements)

References 8 publications

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“…Cell response to the presence of chitosan has been extensively investigated 29,30) . Up-regulation of various types of biologic markers has been reported in the presence of chitosan in several cell culture studies and animal studies [29][30][31][32] . Waltregny et al 26) reported that BSP is an osteoblastic differentiation marker and has functions as a hydroxyapatite nucleator.…”

Section: Discussionmentioning

confidence: 97%

Effect of Chitosan on Expression of Osteogenic Genes during the Healing of Rat Extraction Socket

Youn¹,

Jung²,

Lee³

et al. 2014

Journal of Korean Dental Science

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Section: Discussionmentioning

confidence: 97%

Effect of Chitosan on Expression of Osteogenic Genes during the Healing of Rat Extraction Socket

Youn¹,

Jung²,

Lee³

et al. 2014

Journal of Korean Dental Science

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“…In recent years, a variety of 3D printing technologies have been further developed to construct bone repair at National University of Singapore printed a mesh hydroxyapatite-chitosan structure as bone repair fillers [64] . In 2005, Seitz et al at Germany cooperated with Generis GmbH (Augsburg, Germany) company developed a 3D printed ceramic bone repair material [65] .…”

Section: Large Organ 3d Bioprintingmentioning

confidence: 99%

Progress in organ 3D bioprinting

Fan¹,

Liu²,

Chen³

et al. 2024

IJB

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Three dimensional (3D) printing is a hot topic in today's scientific, technological and commercial areas. It is recognized as the main field which promotes "the Third Industrial Revolution". Recently, human organ 3D bioprinting has been put forward into equity market as a concept stock and attracted a lot of attention. A large number of outstanding scientists have flung themselves into this field and made some remarkable headways. Nevertheless, organ 3D bioprinting is a sophisticated manufacture procedure which needs profound scientific/technological backgrounds/knowledges to accomplish. Especially, large organ 3D bioprinting encounters enormous difficulties and challenges. One of them is to build implantable branched vascular networks in a predefined 3D construct. At present, organ 3D bioprinting still in its infancy and a great deal of work needs to be done. Here we briefly overview some of the achievements of 3D bioprinting technologies in large organ, such as the bone, liver, heart, cartilage and skin, manufacturing.Keywords: organ; 3D bioprinting; bone; heart; liver; cartilage; skin

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“…Ang et al [41] developed a rapid prototyping robotic dispersing (RPBOD) using the same principle as the 3D bio-plotting system, which was used to produce chitosan-HA scaffolds. Solutions of chitosan-HA were extruded into a sodium hydroxide and ethanol medium to induce the precipitation of chitosan.…”

Section: Sff In Tissue Engineeringmentioning

confidence: 99%

State of the art of solid freeform fabrication for soft and hard tissue engineering

Bartolo¹

2006

WIT Transactions on Ecology and the Environment, Vol 87

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Tissue engineering is an interdisciplinary field involving the combined efforts of cell biologists, engineers, material scientists, mathematicians and geneticists towards the development of biological substitutes to restore, maintain, or improve tissue functions. It has emerged as a rapidly expanding field to address the organ shortage problem.Advanced solid freeform fabrication techniques are now being developed to fabricate scaffolds with controlled architecture for tissue engineering. These techniques combine computer-aided design (CAD) with computer-aided manufacturing (CAM) tools to produce three-dimensional structures layer-by-layer in a multitude of materials. This paper introduces the concept of tissue engineering assisted by computer. Different solid freeform fabrication techniques for tissue engineering are described and their advantages and disadvantages discussed with great detail. Novel fabrication procedures, such as alginate rapid prototyping and cell printing, are also presented opening new and exciting possibilities within the tissue engineering field.

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Fabrication of 3D chitosan–hydroxyapatite scaffolds using a robotic dispensing system

Cited by 248 publications

References 8 publications

Effect of Chitosan on Expression of Osteogenic Genes during the Healing of Rat Extraction Socket

Effect of Chitosan on Expression of Osteogenic Genes during the Healing of Rat Extraction Socket

Progress in organ 3D bioprinting

State of the art of solid freeform fabrication for soft and hard tissue engineering

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