Fabrication and characterization of 3-dimensional electrospun poly(vinyl alcohol)/keratin/chitosan nanofibrous scaffold

Islam, Mohammad Tajul; Laing, R. M.; Wilson, Cheryl A.; McConnell, Michelle; Ali, M. Azam

doi:10.1016/j.carbpol.2021.118682

Cited by 39 publications

(18 citation statements)

References 39 publications

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“…These properties were enhanced with the addition of keratin and chitosan. 39 The same research group also utilized the keratin/ chitosan (50:50 w/w) blend to produce surgical sutures with antiinflammatory properties. The scratch assay showed improved cell proliferation and migration in the presence of the sutures, which indicated the potential of the sutures to be used for facilitating wound healing.…”

Section: Keratinmentioning

confidence: 99%

“…Keratin (5% w/v) and chitosan (2% w/v)‐based PVA nanofibrous scaffolds have been reported to exhibit desirable tensile strength, swelling ratio, and porosity. These properties were enhanced with the addition of keratin and chitosan 39 . The same research group also utilized the keratin/chitosan (50:50 w/w) blend to produce surgical sutures with anti‐inflammatory properties.…”

Section: Polymeric Materialsmentioning

confidence: 99%

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A review of current advancements for wound healing: Biomaterial applications and medical devices

2022

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Wound healing is a complex process that is critical in restoring the skin's barrier function. This process can be interrupted by numerous diseases resulting in chronic wounds that represent a major medical burden. Such wounds fail to follow the stages of healing and are often complicated by a pro‐inflammatory milieu attributed to increased proteinases, hypoxia, and bacterial accumulation. The comprehensive treatment of chronic wounds is still regarded as a significant unmet medical need due to the complex symptoms caused by the metabolic disorder of the wound microenvironment. As a result, several advanced medical devices, such as wound dressings, wearable wound monitors, negative pressure wound therapy devices, and surgical sutures, have been developed to correct the chronic wound environment and achieve skin tissue regeneration. Most medical devices encompass a wide range of products containing natural (e.g., chitosan, keratin, casein, collagen, hyaluronic acid, alginate, and silk fibroin) and synthetic (e.g., polyvinyl alcohol, polyethylene glycol, poly[lactic‐co‐glycolic acid], polycaprolactone, polylactic acid) polymers, as well as bioactive molecules (e.g., chemical drugs, silver, growth factors, stem cells, and plant compounds). This review addresses these medical devices with a focus on biomaterials and applications, aiming to deliver a critical theoretical reference for further research on chronic wound healing.

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Section: Keratinmentioning

confidence: 99%

Section: Polymeric Materialsmentioning

confidence: 99%

A review of current advancements for wound healing: Biomaterial applications and medical devices

2022

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“…Electrospinning is a technique used for micro- and nanoscale fiber production from an electrically forced solution/melt of polymeric biomaterials [ 70 ]. The four basic elements required to implement electrospinning are a dosing pump with a syringe (containing the polymer solution), a needle (Taylor cone), a collector drum (can be a plate, metal screen, or rotating mandrel), and a high-voltage power supply (up to 30 kV).…”

Section: Biofabrication Approaches Used To Develop Artificial Scaffoldsmentioning

confidence: 99%

“…Advantages: simple methodology, relatively low preparation cost, sample uniformity, generation of aligned fibers smaller than a micrometer, scaffold incrementation of surface-to-volume ratio (it improves cell attachment, proliferation, and differentiation), tunable porosity interconnectivity over 80%, unique pore shapes, and superior mechanical properties [ 70 , 71 , 75 , 76 ];…”

Section: Biofabrication Approaches Used To Develop Artificial Scaffoldsmentioning

confidence: 99%

Artificial Scaffolds in Cardiac Tissue Engineering

Roacho-Pérez

Garza-Treviño

Moncada‐Saucedo

et al. 2022

Life

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Cardiovascular diseases are a leading cause of death worldwide. Current treatments directed at heart repair have several disadvantages, such as a lack of donors for heart transplantation or non-bioactive inert materials for replacing damaged tissue. Because of the natural lack of regeneration of cardiomyocytes, new treatment strategies involve stimulating heart tissue regeneration. The basic three elements of cardiac tissue engineering (cells, growth factors, and scaffolds) are described in this review, with a highlight on the role of artificial scaffolds. Scaffolds for cardiac tissue engineering are tridimensional porous structures that imitate the extracellular heart matrix, with the ability to promote cell adhesion, migration, differentiation, and proliferation. In the heart, there is an important requirement to provide scaffold cellular attachment, but scaffolds also need to permit mechanical contractility and electrical conductivity. For researchers working in cardiac tissue engineering, there is an important need to choose an adequate artificial scaffold biofabrication technique, as well as the ideal biocompatible biodegradable biomaterial for scaffold construction. Finally, there are many suitable options for researchers to obtain scaffolds that promote cell–electrical interactions and tissue repair, reaching the goal of cardiac tissue engineering.

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“…Current nanotechnology research developments have enabled the production of nanofibers in textile research, such as electrospinning technology for the production of nanofibrous mat [78]. One such work was the pigment coloration of cellulose nanofibers.…”

Section: Nanotechnology In Pigment Colorationmentioning

confidence: 99%

Pigment Coloration Research Published in the Science Citation Index Expanded from 1990 to 2020: A Systematic Review and Bibliometric Analysis

et al. 2022

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A systematic review and bibliometric study were undertaken utilizing the Science Citation Index Expanded database from 1990 to 2020 to obtain insights into the trajectory of pigment coloration research. The study focused on the publication performance in terms of the yearly production and citations, as well as mainstream journals, categories of the Web of Sciences, leading nations, well-known institutions, and research trends. The survey found that the yearly output of scholarly publications on pigment coloration research climbed gradually throughout the first quarter of the study period and then increased substantially in the latter five years. The present research emphasis and future trends were examined after summarizing the paper title and abstract analyses, author keyword analysis, and the most regularly used keywords derived from words in KeyWords Plus. To expand its reach in numerous application areas, pigment coloration research will continue to focus on improving pigment qualities.

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Fabrication and characterization of 3-dimensional electrospun poly(vinyl alcohol)/keratin/chitosan nanofibrous scaffold

Cited by 39 publications

References 39 publications

A review of current advancements for wound healing: Biomaterial applications and medical devices

A review of current advancements for wound healing: Biomaterial applications and medical devices

Artificial Scaffolds in Cardiac Tissue Engineering

Pigment Coloration Research Published in the Science Citation Index Expanded from 1990 to 2020: A Systematic Review and Bibliometric Analysis

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