J. Neurosci. Res. volume 86, issue 4, P821-831 2008 DOI: 10.1002/jnr.21539 View full text
Chiara Milanese, Ferdinando Fiumara, Antonella Bizzoca, Carlo Giachello, Gerd Leitinger, Gianfranco Gennarini, Pier Giorgio Montarolo, Mirella Ghirardi

Abstract: AbstractBy using antibodies against mouse F3/contactin, we found immunologically related glycoproteins expressed in the nervous tissue of the snail Helix pomatia. Helix contactin-related proteins (HCRPs) include different molecules ranging in size from 90 to 240 kD. Clones isolated from a cDNA expression library allowed us to demonstrate that these proteins are translated from a unique 6.3-kb mRNA, suggesting that their heterogeneity depends on posttranslational processing. This is supported by the results of…

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