Eye Movements in Friedreich's Ataxia

458: Vestibular, saccadic and fixation abnormalities in genetically confirmed Friedreich Ataxia

“…The historical literature on ocular motor pathology presents strict definitions regarding SWJ duration (Dell'Osso et al, 1975). The current data supports previous studies in both FRDA (Dale et al, 1978;Furman et al, 1983;Spieker et al, 1995) and neurologically normal individuals (Abadi and Gowen, 2004) that indicate traditional definitions of SWJ duration are too narrow. As shown in Fig.…”

458: Vestibular, saccadic and fixation abnormalities in genetically confirmed Friedreich Ataxia

“…The historical literature on ocular motor pathology presents strict definitions regarding SWJ duration (Dell'Osso et al, 1975). The current data supports previous studies in both FRDA (Dale et al, 1978;Furman et al, 1983;Spieker et al, 1995) and neurologically normal individuals (Abadi and Gowen, 2004) that indicate traditional definitions of SWJ duration are too narrow. As shown in Fig.…”

Clinical features of Friedreich's ataxia: classical and atypical phenotypes

“…Furman et al . () also found evidence of an oblique component to SWJs and some rare vertical SWJs. The amplitude of refixation abnormality can vary up to 15° with latency up to 500 ms.…”

“…Probably the commonest feature is fixation instability interrupted by involuntary saccades, or square wave jerks (SWJs), which can occur in primary position, horizontal or vertical fixation. These were found in all patients by Furman et al (1983) and Fahey et al (2008), and in 69% of cases by Sch€ ols et al (1997). Furman et al (1983) also found evidence of an oblique component to SWJs and some rare vertical SWJs.…”

“…These were found in all patients by Furman et al (1983) and Fahey et al (2008), and in 69% of cases by Sch€ ols et al (1997). Furman et al (1983) also found evidence of an oblique component to SWJs and some rare vertical SWJs. The amplitude of refixation abnormality can vary up to 15°with latency up to 500 ms.…”

“…Furman et al . () also found impaired visual–vestibular interactions as measured by optokinetic drum assessment and vestibular‐ocular reflex in light and dark after revolving chair. Ptosis is found in a small but significant proportion of cases, perhaps 5–10% (Filla et al .…”

458: Vestibular, saccadic and fixation abnormalities in genetically confirmed Friedreich Ataxia

“…The historical literature on ocular motor pathology presents strict definitions regarding SWJ duration (Dell'Osso et al, 1975). The current data supports previous studies in both FRDA (Dale et al, 1978;Furman et al, 1983;Spieker et al, 1995) and neurologically normal individuals (Abadi and Gowen, 2004) that indicate traditional definitions of SWJ duration are too narrow. As shown in Fig.…”

Clinical features of Friedreich's ataxia: classical and atypical phenotypes

“…Furman et al . () also found evidence of an oblique component to SWJs and some rare vertical SWJs. The amplitude of refixation abnormality can vary up to 15° with latency up to 500 ms.…”

“…Probably the commonest feature is fixation instability interrupted by involuntary saccades, or square wave jerks (SWJs), which can occur in primary position, horizontal or vertical fixation. These were found in all patients by Furman et al (1983) and Fahey et al (2008), and in 69% of cases by Sch€ ols et al (1997). Furman et al (1983) also found evidence of an oblique component to SWJs and some rare vertical SWJs.…”

“…These were found in all patients by Furman et al (1983) and Fahey et al (2008), and in 69% of cases by Sch€ ols et al (1997). Furman et al (1983) also found evidence of an oblique component to SWJs and some rare vertical SWJs. The amplitude of refixation abnormality can vary up to 15°with latency up to 500 ms.…”

“…Furman et al . () also found impaired visual–vestibular interactions as measured by optokinetic drum assessment and vestibular‐ocular reflex in light and dark after revolving chair. Ptosis is found in a small but significant proportion of cases, perhaps 5–10% (Filla et al .…”

458: Vestibular, saccadic and fixation abnormalities in genetically confirmed Friedreich Ataxia

“…The historical literature on ocular motor pathology presents strict definitions regarding SWJ duration (Dell'Osso et al, 1975). The current data supports previous studies in both FRDA (Dale et al, 1978;Furman et al, 1983;Spieker et al, 1995) and neurologically normal individuals (Abadi and Gowen, 2004) that indicate traditional definitions of SWJ duration are too narrow. As shown in Fig.…”

Clinical features of Friedreich's ataxia: classical and atypical phenotypes

“…Furman et al . () also found evidence of an oblique component to SWJs and some rare vertical SWJs. The amplitude of refixation abnormality can vary up to 15° with latency up to 500 ms.…”

“…Probably the commonest feature is fixation instability interrupted by involuntary saccades, or square wave jerks (SWJs), which can occur in primary position, horizontal or vertical fixation. These were found in all patients by Furman et al (1983) and Fahey et al (2008), and in 69% of cases by Sch€ ols et al (1997). Furman et al (1983) also found evidence of an oblique component to SWJs and some rare vertical SWJs.…”

“…These were found in all patients by Furman et al (1983) and Fahey et al (2008), and in 69% of cases by Sch€ ols et al (1997). Furman et al (1983) also found evidence of an oblique component to SWJs and some rare vertical SWJs. The amplitude of refixation abnormality can vary up to 15°with latency up to 500 ms.…”

“…Furman et al . () also found impaired visual–vestibular interactions as measured by optokinetic drum assessment and vestibular‐ocular reflex in light and dark after revolving chair. Ptosis is found in a small but significant proportion of cases, perhaps 5–10% (Filla et al .…”