Extramedullary plasmacytoma of the breast: An unusual diagnosis

Martínez, Carolina; Navarro, Ignacio Madrazo; Porras, Arnau; Cansado, Pilar; Sebastián, Antonio Arroyo

doi:10.1111/tbj.13990

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2021

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“…Polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes, adenopathy and extensive skin patch overlying a plasmacytoma are paraneoplastic syndromes associated with plasma cell neoplasms[ 3 ]. To date, extramedullary plasmacytoma located on both sides of the breast have been reported, and pathological examination confirmed the existence of plasma cell infiltration in the breast[ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Infiltrating ductal breast carcinoma with monoclonal gammopathy of undetermined significance: A case report

Ma¹,

Cui²,

Yin³

2021

WJCC

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BACKGROUND Infiltrating ductal breast carcinoma with monoclonal gammopathy of undetermined significance (MGUS) is rare and easily misdiagnosed. Most patients are first diagnosed with MGUS. We report a rare case of MGUS secondary to infiltrating ductal breast carcinoma. We also review the literature to analyze the clinical characteristics and diagnostic methods. CASE SUMMARY A 51-year-old woman underwent modified radical mastectomy for infiltrating ductal carcinoma of the right breast and was then treated with radiation and chemotherapy. A decreased platelet count was found on routine blood examination, and MGUS was subsequently diagnosed. This is the first report of the occurrence of MGUS after breast cancer surgery. CONCLUSION Vigilance is required to distinguish this rare comorbidity from breast plasmacytoma.

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Section: Introductionmentioning

confidence: 99%