Extramammary Paget's Disease with Metastasis to Lymph Nodes

Prose, Philip H.

doi:10.1001/archderm.1959.01560220008002

Cited by 6 publications

(1 citation statement)

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“…A comprehensive review by Treves 2 drew attention to earlier reports of dermatitis of the nipple/areola that could precede cancer of the female breast (Velpeau in 1840) and even earlier reports of Paget’s disease in the nipple of a man by John of Arderne early in the 14th century. Extramammary Paget’s disease (EPD) histologically showing characteristic Paget cells was first described by Radcliffe Crooker in 1889 (according to Prose and Hyman) 3 …”

Section: Commentmentioning

confidence: 99%

Pigmented mammary Paget’s disease: not a melanoma

Al-Daraji

O’Shea

Looi³

et al. 2009

Histopathology

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case summaryThe patient was a hitherto fit and well 57-year-old Chinese woman with a history of a pigmented plaque over her nipple and areola for 12 months, which had been slowly increasing in size. Physical examination, including breast examination, was unremarkable except for an area of hyperpigmentation in the nipple region, which was completely excised following initial biopsy. histopathologyThe biopsy and resection specimens demonstrated similar histological features. Sections showed an intra-epidermal proliferation of large atypical tumour cells, with round or oval nuclei and prominent nucleoli arranged either as solitary units or as nests along and A B

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Section: Commentmentioning

confidence: 99%