Extraction Products from Tobacco – Aroma and Bioactive Compounds and Activities

Popova, Venelina; Gochev, Velizar; Girova, Tanya; Iliev, Ivan; Ivanova, Tanya; Stoyanova, Albena

doi:10.2174/157340721101150804150016

Cited by 21 publications

(29 citation statements)

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“…Our results, however, supported previous findings stating that each of the aromatic products, common to the fragrance industry, i.e., EO, concrete, and resinoid, isolated from a given plant matrix, has a unique composition shaped by the factors involved in the isolation process, namely temperature, duration, selectivity of the solvent, and others [33]. The results also confirmed our previous observations about the differentiation of the aromatic products obtained from other Nicotiana species, different types and varieties of N. tabacum [32,38,39] and N. alata [40]. As seen in Table 1, only the EO of N. glutinosa contained carotenoid-related fragrance compounds, e.g., α-ionone (1.6%), 3,4-dehydro-β-ionone (2.1%), and trans-β-damascenone (1.6%), which was similar to our previous results on N. tabacum aromatic products [39] and the influence of pH, temperature, and duration of hydrodistillation on carotenoid degradation.…”

Section: Discussionsupporting

confidence: 87%

“…The yield of the EO, 0.23 ± 0.50% DW, was in the range cited in previous reports on N. tabacum (0.2-1.5%) [31]. The yield of concrete, 1.56 ± 0.13% DW, was also comparable to the yield of concrete obtained from N. tabacum "Krumovgrad 90" variety of oriental tobacco (1.6%) [32]. In turn, the yield of resinoid, 10.6 ± 0.09% DW, was lower than that reported for various types and origins of common tobacco, e.g., 12%-17% [31] or 14%-29% [32], but still reasonably high.…”

Section: Discussionsupporting

confidence: 82%

“…The results from the olfactory evaluation supports the eventual interest in N. glutinosa aromatic products, as contemporary fragrance industry is searching for distinct tobacco notes in masculine perfumery and cosmetics, for green notes in unisex products, and for balsamic and honey-like notes in fragrances for women, especially those of the "brunette" type. The relative distribution of chemical compounds supported the findings that polar solvents (ethanol) readily extracted plant alkaloids (34.6% share in N. glutinosa resinoid), while the distillation from an acidic medium (in the case of the EO) or the use of non-polar solvents (n-hexane, for concrete) resulted in minimal alkaloid transition to the final product [32,38,40]. The high alkaloid concentration in N. glutinosa resinoid, together with the presence of some compounds with antioxidant potential, suggested that future investigation of the aromatic product might prove its potential for use in hair-treatment cosmetic products (gels, lotions, etc.…”

Section: Discussionsupporting

confidence: 64%

“…Molecules 2019, 24, x 3 of 17 fluid extracts are widely used in fine perfumery and cosmetics [31][32][33]. Therefore, it seemed rational to attempt a similar look on N. glutinosa.…”

Section: Resultsmentioning

confidence: 99%

“…The last decades, however, have been witnessing an intensive search for novel plant sources to expand the range of natural EOs and extraction concentrates from aromatic and medicinal plants available to meet the ever-increasing demands of the fragrance market. Common tobacco (N. tabacum) and some other Nicotiana species (for example, its Australian relative N. benthamiana Domin) are legitimate medicinal plants, and tobacco absolute, concrete, and supercritical fluid extracts are widely used in fine perfumery and cosmetics [31][32][33]. Therefore, it seemed rational to attempt a Molecules 2020, 25, 30…”

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confidence: 99%

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Terpenoids in the Essential Oil and Concentrated Aromatic Products Obtained from Nicotiana glutinosa L. Leaves

et al. 2019

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N. glutinosa L. is a relatively less studied Nicotiana species (Solanaceae), although there are data about its importance as a model plant in viral control studies, as a gene donor in tobacco hybridization and as a source of agents with insecticidal or fungicidal effects. The biological activities of the species were associated mostly with the presence of leaf surface metabolites, in particular diterpenes and sucrose esters. The aim of this study was to identify the chemical composition of the essential oil (EO) and two aromatic extraction products (concrete and resinoid) obtained from N. glutinosa L. leaves. GC-MS analysis identified 26 components in the EO (representing 97.3% of total oil content), which contained mostly diterpene compounds with major components manool (14.2%), sclarene (8.4%) and manoyl oxide (8.1%). The number of compounds identified in the concrete was 37 (95.5% of the total content) and the major component was the diterpene alcohol sclareol (14.2%). In the resinoid, 30 volatile components (representing 95.1% of resinoid content) were identified, with major components nicotine (32.9%), α-tocopherol (8.2%), tridecanoin (6.9%), sclareol (6.9%), and solanone (6.9%). The group of bicyclic diterpenes had the largest share in the diterpene fraction of the products (57.3%, 91.7%, and 86.3%, respectively for the EO, concrete, and resinoid). Considering the abundance of sclareol in the aromatic products, the antimicrobial activity of the pure substance was determined. Sclareol was highly effective against a set of medicinally important yeasts; Candida albicans AТCC 10231, C. glabrata ATCC 90030, C. parapsilosis clinical isolate, and C. tropicalis NBIMCC 23, while being less effective against the studied Gram-positive and Gram-negative bacteria. Data from the study on N. glutinosa aromatic products composition may be of interest to the aroma industries for their possible use in perfumery and cosmetics.Molecules 2020, 25, 30 2 of 16 N. glutinosa is native to Northern and Central Peru and Southern Ecuador, where it has adapted well to semi-arid areas, rocky slopes and ditch banks [1,5]. Plants are more fragile and with tender stem than common tobacco (N. tabacum), rarely branching [6]. Leaves are petiolate, heart-shaped; with a maximum length of about 23 cm. Inflorescences are racemose with long peduncles. Unlike N. tabacum, the flowers of N. glutinosa tend to form bilabiate corolla and are deep orange in color with long anthers adhering to the upper lobe of the corolla, as in the bilabiate flowers of other families [6]. N. glutinosa germinates readily and grows well in both a greenhouse and the field [7]. There are three accessions of N. glutinosa, labeled as accessions (acc.) 24, 24A, and 24B [8].Data on the chemical composition of N. glutinosa leaves are generally limited [5], with the exception of those for alkaloids, as well as for sucrose esters, diterpene alcohols and other leaf surface exudate components [8][9][10][11][12][13][14][15]. The major alkaloid in N. glutinosa is nornicotine [16], alth...

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Section: Discussionsupporting

confidence: 87%

Section: Discussionsupporting

confidence: 82%

Section: Discussionsupporting

confidence: 64%

“…Molecules 2019, 24, x 3 of 17 fluid extracts are widely used in fine perfumery and cosmetics [31][32][33]. Therefore, it seemed rational to attempt a similar look on N. glutinosa.…”

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

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Terpenoids in the Essential Oil and Concentrated Aromatic Products Obtained from Nicotiana glutinosa L. Leaves

et al. 2019

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Volatile organic compounds of tobacco leaves versus waste (scrap, dust, and midrib): extraction and optimization

et al. 2020

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BACKGROUND Volatile organic compounds are present at very low concentration but exhibit an important influence on flavor and aroma of tobacco leaves and products. During tobacco processing, at different stages, tobacco wastes occur. Since they are delivered directly from the tobacco plant, they are expected to have a similar aroma profile. RESULTS The volatile composition of three types of tobacco waste (scrap, dust, and midrib) was characterized for the first time and compared with tobacco leaves’ volatile composition. Ultrasound‐assisted extraction with hexane followed by gas chromatography–mass spectrometry was successfully applied. Different ultrasound‐assisted extraction parameters (temperature, time, and solvent:solid ratio) showed a significant influence on the volatile profiles of the extracts obtained. The most important compounds in tobacco leaves, scrap, and dust with the highest abundance were nicotine (up to 87.5%), 4,8,13‐duvatriene‐1,3‐diol (up to 16.2%), and neophytadiene (up to 9.4%). In midrib, only nicotine was present in all extracts. The most abundant compounds in the extracts were quantified and subjected to optimization using response surface methodology. CONCLUSION Regression analysis showed that 83–98% of the variation was explained by the models obtained. The experimentally obtained values agreed with those predicted, thus indicating the suitability of the model employed and the success of response surface methodology in optimizing the extraction conditions. © 2020 Society of Chemical Industry

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Current advances of functional phytochemicals in Nicotiana plant and related potential value of tobacco processing waste: A review

Zou

Abu-Izneid

et al. 2021

Biomedicine & Pharmacotherapy

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Extraction Products from Tobacco – Aroma and Bioactive Compounds and Activities

Cited by 21 publications

References 0 publications

Terpenoids in the Essential Oil and Concentrated Aromatic Products Obtained from Nicotiana glutinosa L. Leaves

Terpenoids in the Essential Oil and Concentrated Aromatic Products Obtained from Nicotiana glutinosa L. Leaves

Volatile organic compounds of tobacco leaves versus waste (scrap, dust, and midrib): extraction and optimization

Current advances of functional phytochemicals in Nicotiana plant and related potential value of tobacco processing waste: A review

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