Extracellular transport properties of Aplysia californica intestine

Energetics of Potassium Ion Transport in Aplysia Gut

“…The increased Na + flux, and concomitant increased intracellular Na + activity, would then stimulate an extracellular serosal to cytosol K + flux (Table 3) which is mediated by a ouabain-sensitive Na + /K + -ATPase as is also shown in Table 3. Since it has been shown that the major portion of the SCC before and after AIB addition to the mucosal solution is a Clcurrent (Gerencser, 1981b) which is generated by a Clpump (Gerencser, 1996) there would be a decrease in the negativity of Ψ s by both the additive increased electrogenic Na + /K + -and Cl -pump activities; and, the linkage of Ψ m to Ψ s through a low resistance extracellular shunt (Gerencser and Loughlin, 1983) which would lead to a greater serosally-negative Ψ ms (Schultz, 1977) as shown in Table 1. When AIB is present in the mucosal bathing solution the against which the Na + /K + pump is moving Na + out of the cell across the BLM decreases significantly relative to across the BLM in the absence of AIB, as is shown in Table 1.…”

Energetics of Potassium Ion Transport in Aplysia Gut

“…The increased Na + flux, and concomitant increased intracellular Na + activity, would then stimulate an extracellular serosal to cytosol K + flux (Table 3) which is mediated by a ouabain-sensitive Na + /K + -ATPase as is also shown in Table 3. Since it has been shown that the major portion of the SCC before and after AIB addition to the mucosal solution is a Clcurrent (Gerencser, 1981b) which is generated by a Clpump (Gerencser, 1996) there would be a decrease in the negativity of Ψ s by both the additive increased electrogenic Na + /K + -and Cl -pump activities; and, the linkage of Ψ m to Ψ s through a low resistance extracellular shunt (Gerencser and Loughlin, 1983) which would lead to a greater serosally-negative Ψ ms (Schultz, 1977) as shown in Table 1. When AIB is present in the mucosal bathing solution the against which the Na + /K + pump is moving Na + out of the cell across the BLM decreases significantly relative to across the BLM in the absence of AIB, as is shown in Table 1.…”

Energetics of Potassium Ion Transport in Aplysia Gut

“…The increased Na + flux, and concomitant increased intracellular Na + activity, would then stimulate an extracellular serosal to cytosol K + flux (Table 3) which is mediated by a ouabain-sensitive Na + /K + -ATPase as is also shown in Table 3. Since it has been shown that the major portion of the SCC before and after AIB addition to the mucosal solution is a Clcurrent (Gerencser, 1981b) which is generated by a Clpump (Gerencser, 1996) there would be a decrease in the negativity of Ψ s by both the additive increased electrogenic Na + /K + -and Cl -pump activities; and, the linkage of Ψ m to Ψ s through a low resistance extracellular shunt (Gerencser and Loughlin, 1983) which would lead to a greater serosally-negative Ψ ms (Schultz, 1977) as shown in Table 1. When AIB is present in the mucosal bathing solution the against which the Na + /K + pump is moving Na + out of the cell across the BLM decreases significantly relative to across the BLM in the absence of AIB, as is shown in Table 1.…”

Energetics of Potassium Ion Transport in Aplysia Gut

“…The increased Na + flux, and concomitant increased intracellular Na + activity, would then stimulate an extracellular serosal to cytosol K + flux (Table 3) which is mediated by a ouabain-sensitive Na + /K + -ATPase as is also shown in Table 3. Since it has been shown that the major portion of the SCC before and after AIB addition to the mucosal solution is a Clcurrent (Gerencser, 1981b) which is generated by a Clpump (Gerencser, 1996) there would be a decrease in the negativity of Ψ s by both the additive increased electrogenic Na + /K + -and Cl -pump activities; and, the linkage of Ψ m to Ψ s through a low resistance extracellular shunt (Gerencser and Loughlin, 1983) which would lead to a greater serosally-negative Ψ ms (Schultz, 1977) as shown in Table 1. When AIB is present in the mucosal bathing solution the against which the Na + /K + pump is moving Na + out of the cell across the BLM decreases significantly relative to across the BLM in the absence of AIB, as is shown in Table 1.…”