Extracellular Matrices In Gynecological Surgery – Literature Review

Banacu, Mihail; Socea, Bogdan; Pelinaru, Adrian; Lascăr, Ioan; Pharmacy, Bucharest

doi:10.31688/abmu.2020.55.2.14

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…Human acellular dermal matrices (ADMs) can be used successfully in gynecological reconstructive surgery [ 41 , 42 ]. Ward et al conducted a retrospective analysis of thirty-three women suffering from recurrent stage II anterior vaginal dislocations or primary or recurrent stage III-IV vaginal dislocations who underwent paravaginal vaginal reconstruction using commercially available AlloDerm between the years of 1998 -2002.…”

Section: Reconstructive Gynecologymentioning

confidence: 99%

Human Acellular Dermal Matrix in Reconstructive Surgery—A Review

Gierek¹,

Łabuś²,

Kitala³

et al. 2022

Biomedicines

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Reconstructive surgery often confronts large tissue defects. This creates a need to look for materials that are immunogenic but offer the possibility of tissue filling. ADM—acellular dermal matrix—is a biological collagen matrix without immunogenicity, which is more commonly used in surgical treatment. Reconstructive surgery is still searching for various biocompatible materials that can be widely used in surgery. The available materials have their advantages and disadvantages. This paper is a literature review on the use of human acellular dermal matrix (ADM) in reconstructive surgery (surgical oncology, plastic and reconstructive surgery, and gynecologic reconstructive surgery). ADM appears to be a material of increasing use in various fields of surgery, and thus, further research in this area is required.

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Section: Reconstructive Gynecologymentioning

confidence: 99%

Human Acellular Dermal Matrix in Reconstructive Surgery—A Review

Gierek¹,

Łabuś²,

Kitala³

et al. 2022

Biomedicines

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show abstract

“…Although many sources emphasize that a significant part of the complications experienced result from wrong qualification or the wrong selection of an implant for a static defect, the interest in this method has weakened. The most common complications after this type of surgery include the erosion of the mesh into the vagina, bladder or rectum, the recurrence of prolapse, pelvic pain syndrome, dyspareunia, vaginal stenosis and/or shortening, and postoperative fistulas [ 1 , 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Application of Acellular Dermal Matrix in Gynaecology—A Current Review

Skowronek

Łabuś

Stojko

et al. 2022

JCM

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The aim of our study is to draw attention to the multitude of applications of acellular dermal matrix (ADM) in the surgical treatment of urogynaecological disorders, such as reduction in the reproductive organs, and in reconstructive gynaecology. Despite the existence of numerous operational methods and materials, the effectiveness of transvaginal operation is still insufficient. Native tissue operations are often not durable enough, while operations with synthetic materials have numerous side effects, such as infections, hematomas, vaginal erosion, or dyspareunia. Hence, the search continues for a different material with a better efficacy and safety profile than those previously mentioned. It seems that ADM can meet these requirements and be a useful material for urogynaecological surgery. Key words related to the usage of ADM in gynaecological reconstructive surgery were used to search relevant databases (NCBI MedLine, Clinical Key, Clinicaltrials.gov). This manuscript is based on 43 literature sources, 28 (65.11%) of which were released after 2016. Older sources are cited for the purpose of presenting basic science, or other important issues related to the manuscript. ADM seems to be an ideal material for urogynaecological and reconstructive surgery. It has high durability, and thus high effectiveness. Moreover, it does not have the side effects typical for synthetic materials. There are no reports of material rejection, erosion or dyspareunia directly related to the presence of the mesh. Due to the difficulties in obtaining ADM and the need to perform additional tests, this material is not common in routine clinical practice. Therefore, the number of cases and the size of the research groups are insufficient to clearly define the potential of mesh from biological tissue. However, the results are so promising that it is worth considering a wider introduction to the use of this material. Our hope is that increasing clinicians’ awareness of this topic will lead to more studies comparing methods using native tissues or synthetic materials and those using ADM.

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Extracellular Matrices In Gynecological Surgery – Literature Review

Abstract: Matrices extracellulaires en chirurgie gynécologique -revue de la littérature

Cited by 2 publications

References 29 publications

Human Acellular Dermal Matrix in Reconstructive Surgery—A Review

Human Acellular Dermal Matrix in Reconstructive Surgery—A Review

Application of Acellular Dermal Matrix in Gynaecology—A Current Review

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