Extensive versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyps and Asthma: A 1-year Study

Chen, Fenghong; Deng, Jie; Hong, Haiyu; Xu, Rui; Guo, Jialong; Hou, Wei; Sun, Yueqi; Lai, Yinyan; Li, Hua-Bin; Shi, Jianbo

doi:10.2500/ajra.2016.30.4271

Cited by 59 publications

(66 citation statements)

References 34 publications

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“…During follow‐up, significantly more patients within the CRSwNP cohort underwent endoscopy or had a CT scan versus the reference group (60.4% vs. 0.2% and 69.1% vs. 0.4, respectively; both P < .001), which correlates with the use of endoscopy and CT scans for clinical assessment and diagnosis of CRSwNP. In the US, FESS is widely considered the standard surgical intervention for CRSwNP, and in this study, 42.7% of patients with CRSwNP underwent FESS. A previous study of patients with CRS found that 46.2% underwent endoscopic sinus surgery; therefore, although our results were as expected, we believe that this is one of the first times such data have been reported in patients with CRSwNP specifically.…”

Section: Discussionmentioning

confidence: 84%

Cost burden and resource utilization in patients with chronic rhinosinusitis and nasal polyps

Villeneuve²,

et al. 2019

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Objectives/Hypothesis Establish treatment patterns and economic burden in US patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) versus without chronic rhinosinusitis (CRS). Determine comparative costs of subgroups with high clinical burden. Study Design Observational, retrospective, case‐control study. Methods This study matched patients with CRSwNP to patients without CRS (1:1) using the Truven Health MarketScan US claims database. Categorical and continuous variables were compared using McNemar test and paired t test (normal distribution) or Wilcoxon signed rank tests (non‐normal distribution). Within subgroups, χ2 and Wilcoxon or t tests were used (normal distribution). Results There were 10,841 patients with CRSwNP and 10,841 patients without CRS included. Mean age in the CRSwNP cohort was 45.8 years; 56.2% were male. During follow‐up, patients with CRSwNP had an increased diagnosis of asthma versus patients without CRS (20.8% vs. 8.1%, respectively; P < .001). Annual incremental costs were $11,507 higher for patients with CRSwNP versus those without CRS. Costs were higher in subgroups of patients with CRSwNP undergoing functional endoscopy sinus surgery (FESS), with a comorbid diagnosis of asthma, receiving oral corticosteroids, or macrolides versus the overall CRSwNP group. Patients with CRSwNP undergoing FESS had the highest costs of the four subgroups ($26,724, $22,456, $20,695, and $20,990, respectively). Conclusions Annual incremental costs were higher among patients with CRSwNP versus without CRS. Patients with CRSwNP with high clinical burden had higher overall costs than CRSwNP patients without. Level of Evidence NA Laryngoscope, 129:1969–1975, 2019

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Section: Discussionmentioning

confidence: 84%

Cost burden and resource utilization in patients with chronic rhinosinusitis and nasal polyps

Villeneuve²,

et al. 2019

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“…Philips et al [15] showed that the most common and also recoverable symptom after endoscopic sinus surgery is headache. Chen et al [13] found significant improvement in the VAS score at one year after surgery. Proimos et al [7] found statistically significant improvement after operation in nasal blockage, smell, facial pain and headache.…”

Section: Discussionmentioning

confidence: 95%

Effect of functional endoscopic sinus surgery on asthma control with nasal polyposis and chronic rhinosinusitis

Akdeniz¹,

Dülger²,

Durmaz³

et al. 2017

The European Research Journal

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Objectives. The purpose of this study is to examine the effect of endoscopic sinus surgeons on the control of disease in asthma combined with chronic rhinosinusitis. Methods. Twenty-three asthma patients with chronic rhinosinusitis were evaluated retrospectively. They were assessed with asthma control test and pulmonary function tests. Subjective nasal obstruction assessment was done according to the nasal obstruction symptoms evaluation (NOSE) scale. Other subjective sinonasal complaints were classified using visual analogue scale (VAS). At postoperative third month, pulmonary function tests, asthma control test, NOSE and VAS were reevaluated. Results. According to asthma control test, number of patients under control, partial controlled and uncontrolled were 2/6/15 preoperatively and 14/4/5 postoperatively, respectively. There was permanent or partial improvoment in fullness in the nose sniffle of 95.7% according to NOSE. The most remarkable permanent improvement in the symptoms were seen in the feeling of pressure in the face of 75%, smell disorders of 66.7% according to sinonasal visual analogue scale assessment. NOSE and VAS values were significantly improved postoperatively ( <0.05). Conclusions. Uncontrolled asthma associated with chronic rinosinusitis can benefit from functional endoscopic sinus surgery in asthma control level, nasal blockage symptoms and other sinonasal complaints.

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“…There is some evidence to support a more extensive approach, particularly in eosinophilic disease or CRSwNP (75,76) .…”

Section: Ii) Extent Of Surgerymentioning

confidence: 99%

Prevention of chronic rhinosinusitis

Hopkins

Šurda

Bast

et al. 2018

Rhin

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Extensive versus Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyps and Asthma: A 1-year Study

Abstract: EESS for patients with CRSwNP and with asthma may help to improve the subjective olfaction and endoscopic appearance.

Cited by 59 publications

References 34 publications

Cost burden and resource utilization in patients with chronic rhinosinusitis and nasal polyps

Cost burden and resource utilization in patients with chronic rhinosinusitis and nasal polyps

Effect of functional endoscopic sinus surgery on asthma control with nasal polyposis and chronic rhinosinusitis

Prevention of chronic rhinosinusitis

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