Extensive Cerebral Venous Thrombosis

Nelson, Sarah E.; Ho, Bryan

doi:10.1001/jamaneurol.2013.1952

Cited by 1 publication

(1 citation statement)

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“…In the present study, one patient (5.3%) developed significantly poorer neurological function. The reasons leading to a poorer clinical condition during LMWH treatment in therapeutic dosages may be persistent thrombosis, 10 which is supported by the repeated MRI scan showing fresh venous infarction. In recent years, there are increasing case reports and small case series showing that endovascular mechanical thrombectomy is beneficial for the patients with clinical deterioration despite use of anticoagulation or uncontrolled intracranial hypertension resistant to standard therapy.…”

Section: Discussionmentioning

confidence: 96%

Clinical characteristics of cerebral venous sinus thrombosis

Wang

Song

et al. 2015

NSJ

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Objectives:To investigate the risk factors, clinical presentation, neuroimaging features, treatment, and prognosis of patients with cerebral venous sinus thrombosis (CVST).Methods:We retrospectively analyzed the data of 19 patients with a diagnosis of CVST admitted to Beijing Chao-Yang Hospital affiliated to Capital Medical University, Beijing, China between January 2010 and December 2013.Results:There were 9 men and 10 women (age range: 27-75 years). Headache (84.2%) and focal signs (57.9%) were the 2 most common symptoms. Direct evidence of thrombosis was found on CT in 42.1%, and on MRI in 52.6%. Two or more sinuses were involved in 78.9% of cases, in which the transverse sinus plus sigmoid sinus were the most commonly involved combination. All patients received anticoagulant therapy. Most patients (84.2%) had no neurological sequelae at discharge, and only 3 patients (15.8%) recovered with sequelae.Conclusion:Our study provides detailed information on the clinical manifestations, neuroimages, management, outcome, and risk factors of the patients with CVST.

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Section: Discussionmentioning

confidence: 96%