volume 66, issue 7, P4580-4586 1992
DOI: 10.1128/jvi.66.7.4580-4586.1992
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P Rollini, J Billotte, E Kolb, H Diggelmann

Abstract: To study the tissue specificity of mouse mammary tumor virus (MMTV) gene expression, we developed two series of transgenic mice, containing the MMTV proviral DNA of mammary (GR) and kidney (C3H-K) origin. The expression pattern in the MMTV(GR) transgenic mice is very similar to that observed in infected animals, e.g., a strong preference for viral expression in the lactating mammary glands and lower levels of expression in salivary glands, lymphoid tissues, and male reproductive organs. One line of transgenic …

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