Expression of Semaphorin4C by Th2-stimulated B cells

Abstract

Figure 1 Relative expression of SEMA4C mRNA over GAPDH in stimulated tonsillar B cells (N=5).

Comparison of the efficacy of combined budesonide and fexofenadine versus combined fluticasone propionate and fexofenadine on the expression of class-4 semaphorins and their receptors in the peripheral blood cells of patients with allergic rhinitis

“…Moreover, inhibition of SEMA4A - Plexin-D1 reduced lung fibrosis mediated by AKT (protein kinase B) signaling [ 38 ]. Interestingly, Another survey declared that SEMA4C could be a key player in local allergic inflammation [ 39 ]. It has also been shown that SEMA4A - Plexin-D1 contributed to the elevated IL-4 and IL-17 in patients with systemic sclerosis (SSc), and the same manner can be seen for other T CD4 + mediate diseases, including asthma, rheumatoid arthritis (RA), and multiple sclerosis (MS) [ [40] , [41] , [42] ].…”