Experts Point to Lessons Learned From Controversy Over Rofecoxib Safety

Integrating Pain Management in Clinical Practice

“…Department of Justice, 2006). Physicians continue to struggle with providing the appropriate pain relief for patients, while minimizing the misuse of opioid analgesics (Hampton, 2005). Misuse of pain medications includes selling and diverting prescription drugs, seeking prescriptions from multiple providers, using illicit drugs, snorting or injecting medications, and using drugs in a manner other than the way it was intended.…”

Assessment and Treatment of Abuse Risk in Opioid Prescribing for Chronic Pain

“…Physicians continue to struggle with providing the appropriate pain relief for patients, while minimizing the misuse of opioid analgesics [64]. Misuse of pain medications includes selling and diverting prescription drugs, seeking prescriptions from multiple providers, using illicit drugs, snorting or injecting medications, and using drugs in a manner other than the way it was intended.…”

Light and Fire

“…Though clinical trials do capture medication safety information, recent events indicate that the full scope of adverse events cannot be captured during clinical trials alone. 5 To further complicate matters, in comparison to conventional medications, biologics are large and complex molecules that target the molecular pathogenesis of disease in humans. 6 Though their mechanisms of action may be advantageous in terms of greater specificity, this specificity may warrant reassessing how biologics are developed and tested for safety in humans.…”