Experimental laboratory models as tools for understanding modifiable dementia risk
Duncan Sinclair,
Alison J. Canty,
Jenna M. Ziebell
et al.
Abstract:Experimental laboratory research has an important role to play in dementia prevention. Mechanisms underlying modifiable risk factors for dementia are promising targets for dementia prevention but are difficult to investigate in human populations due to technological constraints and confounds. Therefore, controlled laboratory experiments in models such as transgenic rodents, invertebrates and in vitro cultured cells are increasingly used to investigate dementia risk factors and test strategies which target them… Show more
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