“…By studying yeast phase formation of B. dermatitidis in a chemically defined semifluid medium, Salvin (142) showed that temperature was the most important environmental factor controlling dimorphism in this organism. No amino acid, carbohydrate, nor growth-substance tested was found to be an essential accessory factor for the growth of the yeast phase at 37 C. This evidence was in accord with the findings of previous workers (36,62,84,93,108,111,130). Nickerson and Edwards (111) proposed the term "thermal dimorphism" to characterize this phenomenon.…”