Experimental and theoretical studies of imidazole based chemosensor for Palladium and their biological applications

Suresh, S.; Bhuvanesh, N.; Raman, Arunachalam; Sugumar, P.; Padmanabhan, Dhanasekaran; Easwaramoorthi, Shanmugam; Ponnuswamy, M. N.; Subbiah, Kavitha; Nandhakumar, Raju

doi:10.1016/j.jphotochem.2019.112092

Cited by 16 publications

(4 citation statements)

References 45 publications

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“…3C). 71 The concentration of QĲ7) was fixed at 10 μM while mixing with the filtrate solution (final [PdĲII)] = 25 μM, if there is complete leaching of PdĲII)). Total quenching of QĲ7) fluorescence will be observed if 100% PdĲII) is leached out.…”

Section: Role Of Ligand-metal Complex In the Catalytic Activity Of Na...mentioning

confidence: 99%

Developing Pd(ii) based amphiphilic polymeric nanoparticles for pro-drug activation in complex media

Sathyan

Croke

Pérez

et al. 2022

Mol. Syst. Des. Eng.

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Section: Role Of Ligand-metal Complex In the Catalytic Activity Of Na...mentioning

confidence: 99%

Developing Pd(ii) based amphiphilic polymeric nanoparticles for pro-drug activation in complex media

Sathyan

Croke

Pérez

et al. 2022

Mol. Syst. Des. Eng.

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“…The absorbance intensity of probe V9 was considerably enhanced, the fluorescence emission intensity was quenched in the presence of Pd (II) ions, and the presence of other metal ions had no notable interference. The detection of intracellular Pd (II) ions in living cells was performed using probe V9 on brine shrimp nauplii (Artemia salina), up to 20 μg/mL [ 486 ].…”

Section: Imidazole-based Supermolecules As Pathological Probesmentioning

confidence: 99%

Comprehensive Insights into Medicinal Research on Imidazole-Based Supramolecular Complexes

Tan

Zhang

et al. 2023

Pharmaceutics

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The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two nitrogen atoms, is an important functional fragment widely present in a large number of biomolecules and medicinal drugs; its unique structure is beneficial to easily bind with various inorganic or organic ions and molecules through noncovalent interactions to form a variety of supramolecular complexes with broad medicinal potential, which is being paid an increasing amount of attention regarding more and more contributions to imidazole-based supramolecular complexes for possible medicinal application. This work gives systematical and comprehensive insights into medicinal research on imidazole-based supramolecular complexes, including anticancer, antibacterial, antifungal, antiparasitic, antidiabetic, antihypertensive, and anti-inflammatory aspects as well as ion receptors, imaging agents, and pathologic probes. The new trend of the foreseeable research in the near future toward imidazole-based supramolecular medicinal chemistry is also prospected. It is hoped that this work provides beneficial help for the rational design of imidazole-based drug molecules and supramolecular medicinal agents and more effective diagnostic agents and pathological probes.

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“…In addition to the biological activities, substituted imidazole derivatives found to possess several other applications such as corrosion inhibitors [7], opto-electric [8], metal sensing [9], fluorescent probe [10] and biological imaging [11]. Because of the wide application of substituted imidazole derivatives, it has drawn a considerable attention of the synthetic, medicinal and theoretical chemists during the past few decades [12]. Moreover, computational study now-a-days has reached a stage whereby new scientific information about the target molecule can be easily generated and may enable the researcher to explore the new properties of the compounds under investigation [13].…”

Section: Introductionmentioning

confidence: 99%

Synthesis, physico‐chemical characterization and theoretical exploration of some 2,4,5‐triaryl imidazole derivatives

Chettri¹,

Tamang²,

Rai

et al. 2023

Journal of Heterocyclic Chem

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A series of six 2, 4, 5‐triarylimidazole (IM‐1 to IM‐6) have been prepared by the multi‐component condensation reaction involving benzil, substituted salicylaldehyde and NH4OAc under solvent free condition by using unconventional CuB4O7 catalyst. The compounds were characterized using various analytical and spectroscopic techniques. Furthermore, DFT studies such as optimization of gas phase structure, HOMO‐LUMO energies, Molecular electrostatic potential, NLO properties of these compounds have been investigated. In‐silico molecular docking study of 2, 4, 5‐triarylimidazole derivatives (IM‐1 to IM‐6) have been carried out to ascertain the inhibitory potential of these molecules against a diabetic protein (PDB ID 1IR3). The study showed that the these compounds have remarkable inhibitory potential against the protein 1IR3 with binding energy (ΔG) values for the compounds (IM‐1 to IM‐6) −8.7, −8.4, −8.8, −8.0, −8.9 and −7.8 kcal/mol respectively. In addition, the pharmacokinetic properties (ADMET) of the compounds (IM‐1 to IM‐6) have also been studied.

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Experimental and theoretical studies of imidazole based chemosensor for Palladium and their biological applications

Cited by 16 publications

References 45 publications

Developing Pd(ii) based amphiphilic polymeric nanoparticles for pro-drug activation in complex media

Developing Pd(ii) based amphiphilic polymeric nanoparticles for pro-drug activation in complex media

Comprehensive Insights into Medicinal Research on Imidazole-Based Supramolecular Complexes

Synthesis, physico‐chemical characterization and theoretical exploration of some 2,4,5‐triaryl imidazole derivatives

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