Experimental Acne Varioliformis

Strumia, Max M.

doi:10.1001/archderm.1924.02360300032002

Cited by 7 publications

(3 citation statements)

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“…The lesions typically comprise oedematous, umbilicated papulopustules that undergo central necrosis, crust over and then slowly heal, leaving varioliform scars. Most lesions are excoriated and may be painful or itchy 102–104 …”

Section: Steps To Diagnosismentioning

confidence: 99%

How not to get scar(r)ed: pointers to the correct diagnosis in patients with suspected primary cicatricial alopecia

Harries

Trüeb

Tosti

et al. 2009

British Journal of Dermatology

102

107

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Primary cicatricial alopecias (PCAs) are a rare, but important, group of disorders that cause irreversible damage to hair follicles resulting in scarring and permanent hair loss. They may also signify an underlying systemic disease. Thus, it is of paramount importance that clinicians who manage patients with hair loss are able to diagnose these disorders accurately. Unfortunately, PCAs are notoriously difficult conditions to diagnose and treat. The aim of this review is to present a rational and pragmatic guide to help clinicians in the professional assessment, investigation and diagnosis of patients with PCA. Illustrating typical clinical and histopathological presentations of key PCA entities we show how dermatoscopy can be profitably used for clinical diagnosis. Further, we advocate the search for loss of follicular ostia as a clinical hallmark of PCA, and suggest pragmatic strategies that allow rapid formulation of a working diagnosis.

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Section: Steps To Diagnosismentioning

confidence: 99%

How not to get scar(r)ed: pointers to the correct diagnosis in patients with suspected primary cicatricial alopecia

Harries

Trüeb

Tosti

et al. 2009

British Journal of Dermatology

102

107

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“…In 1924 Strumia demonstrated induction of ANV lesions by intradermal injection of staphylococci and streptococci isolated from a patient's lesion. 352 Clinical improvements have been reported with both culture-determined and empirical antibiotic regimens. 349,351,353 Relapses are common, therefore frequent courses to treat flares, or maintenance therapy, are often required.…”

Section: Treatmentmentioning

confidence: 99%

“…An association between ANV and S. aureus is well documented. In 1924 Strumia demonstrated induction of ANV lesions by intradermal injection of staphylococci and streptococci isolated from a patient’s lesion 352 . Clinical improvements have been reported with both culture‐determined and empirical antibiotic regimens 349,351,353 .…”

Section: Mixed Groupmentioning

confidence: 99%

Management of primary cicatricial alopecias: options for treatment

et al. 2008

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Primary cicatricial alopecias (PCAs) are a poorly understood group of disorders that result in permanent hair loss. Clinically, they are characterized not only by permanent loss of hair shafts but also of visible follicular ostia along with other visible changes in skin surface morphology, while their histopathological hallmark usually (although not always) is the replacement of follicular structures with scar-like fibrous tissue. As hair follicle neogenesis in adult human scalp skin is not yet a readily available treatment option for patients with cicatricial alopecias, the aim of treatment, currently, remains to reduce symptoms and to slow or stop PCA progression, namely the scarring process. Early treatment is the key to minimizing the extent of permanent alopecia. However, inconsistent terminology, poorly defined clinical end-points and a lack of good quality clinical trials have long made management of these conditions very challenging. As one important step towards improving the management of this under-investigated and under-serviced group of dermatoses, the current review presents evidence-based guidance for treatment, with identification of the strength of evidence, and a brief overview of clinical features of each condition. Wherever only insufficient evidence-based advice on PCA management can be given at present, this is indicated so as to highlight important gaps in our clinical knowledge that call for concerted efforts to close these in the near future.

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Multiple Sarcoid-Like Granulomas of the Skin of Undetermined Nature

Klauder¹

1925

Arch Derm Syphilol

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Experimental Acne Varioliformis

Cited by 7 publications

References 0 publications

How not to get scar(r)ed: pointers to the correct diagnosis in patients with suspected primary cicatricial alopecia

How not to get scar(r)ed: pointers to the correct diagnosis in patients with suspected primary cicatricial alopecia

Management of primary cicatricial alopecias: options for treatment

Multiple Sarcoid-Like Granulomas of the Skin of Undetermined Nature

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