Experiences of postmenopausal osteoporosis: a narrative review

Zadjali, Faiza Al; Brooks, Jane; O’Neill, Terence W; Stanmore, Emma

doi:10.1080/09638288.2023.2169770

Cited by 2 publications

(1 citation statement)

References 51 publications

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“…Shared decision-making results in increased patient satisfaction, improved functional status, optimised self-management and better treatment adherence,27 but it requires comprehensive information about osteoporosis, therapeutic options and possible side effects. This information need has been reported,29 30 but its persistence is surprising, as two-thirds of this substrategy’s interventions have been operationalised in IOC 31. Furthermore, the effectiveness of different education programmes has been demonstrated 32…”

Section: Discussionmentioning

confidence: 99%

Osteoporosis care through an Integrated, People-Centred Health Services framework lens: a hybrid qualitative analysis of international patient experiences

2023

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ObjectivesGlobally, patients with osteoporosis have unmet needs in terms of care accessibility, patient-centredness and care comprehensiveness. The WHO developed the Integrated, People-Centred Health Services (IPCHS) framework to reorient and integrate healthcare systems using 5 interdependent strategies and 20 substrategies. Patients’ perspectives with regard to these strategies are poorly understood. We sought to relate patient-experienced gaps in osteoporosis care to the IPCHS strategies and identify key strategies to guide osteoporosis care reforms.Design, setting and participantsQualitative online study of the experiences of international patients with osteoporosis.ProcedureTwo researchers conducted semi-structured interviews in English, Dutch, Spanish and French that were recorded and transcribed verbatim. Patients were categorised according to their countries’ healthcare systems (universal, public/private and private) and fracture status. A hybrid (sequential theory-driven and data-driven) analysis was performed, with the IPCHS framework used for the theory-driven analysis.ResultsThirty-five patients (33 women) from 14 countries participated. Twenty-two patients had universal healthcare and 18 had experienced fragility fractures. Prioritised substrategies overlapped among healthcare systems, with reported shortcomings related primarily to ‘empowering and engaging individuals and families’ and ‘coordinating care’ (at varying levels). Patients with all healthcare types prioritised ‘reorienting care’, with different substrategies prioritised. Patients with private healthcare called for ‘improving funding and reforming payment systems’. Substrategy prioritisation did not differ between those receiving primary and secondary fracture prevention.ConclusionPatients’ experiences with osteoporosis care are universal. Given the current care gaps and associated patient burdens, policymakers should make osteoporosis a(n) (inter)national health priority. Integrated osteoporosis care reforms should focus on patient-reported experiences with and be guided by priorities in IPCHS strategies, taking into account the healthcare system context.

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Section: Discussionmentioning

confidence: 99%

Osteoporosis care through an Integrated, People-Centred Health Services framework lens: a hybrid qualitative analysis of international patient experiences

2023

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Associations between NHHR and Osteoporosis in the US NHANES Elderly Population

Liu,

Wu,

Xiong

et al. 2024

Preprint

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Background Recent research suggests that the ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR) is emerging as a possible marker for various health issues. However, its correlation with osteoporosis has not been explored. This study aims to explore how NHHR is linked to the likelihood of osteoporosis in older individuals. Methods The study examined the connection between NHHR and osteoporosis in people who are 50 years old and above, utilizing information from the 2005–2010 NHANES. Various statistical analyses were performed, including multivariate logistic regression, analysis using restricted cubic splines, and subgroup analyses, while controlling for relevant demographic and clinical factors. Results A total of 5548 individuals were included, with 313 diagnosed with osteoporosis. The examination reveals a notable negative correlation between NHHR and osteoporosis. Individuals in the top quartile of NHHR had a significantly reduced risk of osteoporosis in comparison to those in the bottom quartile [OR 0.63 (95% CI 0.44–0.90, P for trend = 0.004)].The analysis using RCS showed a non-linear connection between NHHR and osteoporosis (P for overall < 0.001, P for nonlinear = 0.008). Subgroup analyses demonstrated consistent findings across various demographic and clinical subgroups. Conclusions In individuals aged 50 and above, there is a significant correlation between elevated NHHR levels and a reduced likelihood of developing osteoporosis. This study demonstrates that NHHR may serve as a valuable marker for assessing osteoporosis risk in this population, suggesting that incorporating NHHR into routine clinical assessments could enhance early detection and prevention strategies for osteoporosis.

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Experiences of postmenopausal osteoporosis: a narrative review

Cited by 2 publications

References 51 publications

Osteoporosis care through an Integrated, People-Centred Health Services framework lens: a hybrid qualitative analysis of international patient experiences

Osteoporosis care through an Integrated, People-Centred Health Services framework lens: a hybrid qualitative analysis of international patient experiences

Associations between NHHR and Osteoporosis in the US NHANES Elderly Population

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