Arch Dermatol
 2001
DOI: 10.1001/archderm.137.9.1236
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Expanding Our Concepts of Mosaic Disorders of Skin

Amy S. Paller1
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Cited by 26 publications

(17 citation statements)
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“…A mutation of the keratin 10 gene was found in keratinocytes from the nevus but not from normal skin 10 . Similar evidence confirming genetic mosaicism has been found in nevus comedonicus and nevus sebaceous as well as in segmental neurofibromatosis 11 . These lesions, together with other findings, are part of distinctive clinical syndromes.…”
Section: Discussionsupporting
confidence: 75%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…A mutation of the keratin 10 gene was found in keratinocytes from the nevus but not from normal skin 10 . Similar evidence confirming genetic mosaicism has been found in nevus comedonicus and nevus sebaceous as well as in segmental neurofibromatosis 11 . These lesions, together with other findings, are part of distinctive clinical syndromes.…”
Section: Discussionsupporting
confidence: 75%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…As a result, a naevus may continue to be asymptomatic throughout life or sporadically induce tumor transformation. 6 The patient presented in this report could not relate the presence of a previous naevus on oral mucosa, but because a naevus is symptoms free and may pass unnoticed throughout the patient's life, this possibility cannot be excluded. Otherwise it may have more than 1 mechanism for hyperpigmentation, but the significance of intratumoral pigmentation remains inexplicable.…”
Section: Discussionmentioning
confidence: 83%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…6 Genetic mosaicism can result from lyonization, somatic mutation, half-chromatid mutation, chromosomal nondisjunction, or chimerism. 7 It is plausible that this pigmentary lesion we have described is also a manifestation of genetic mosaicism, albeit through a different mechanism not occurring along Blaschko's lines.…”
Section: Discussionmentioning
confidence: 83%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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