Exosomal miR-29a-3p in the immune microenvironment of spleen deficiency promotes hepatocellular carcinoma lung metastasis by activating FAM167A-α1-integrin-NF-κB signaling axis
Abstract:Background
Hepatocellular carcinoma (HCC), a common type of cancer, has a strong metastatic ability and poor prognosis. The tumor microenvironment is the “soil” for the occurrence and development of tumors, with exosomes playing an important role in these processes. In traditional Chinese medicine(TCM), the tumor microenvironment corresponds to the internal environment of the syndrome known as spleen deficiency (SD). Numerous studies have shown that exosomes contain high levels of miRNAs, which have been show… Show more
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