1958
DOI: 10.1001/archderm.1958.01560060088018
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Exfoliative Dermatitis as a Complication of Chloroquine (Aralen) Therapy in Rheumatoid Arthritis

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Cited by 12 publications
(3 citation statements)
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“…It may cause pruritic and burning erythematous, discrete, confluent and widespread eruptions. A case of exfoliative dermatitis 20 days after daily intake of 250 mg. of chloroquine was reported by Graniere [46]. The complications subside on diminution of the dose or withdrawal of the drug.…”
Section: G Arb Sim S Scleroderma With Bullous Lesionsmentioning
confidence: 87%
“…It may cause pruritic and burning erythematous, discrete, confluent and widespread eruptions. A case of exfoliative dermatitis 20 days after daily intake of 250 mg. of chloroquine was reported by Graniere [46]. The complications subside on diminution of the dose or withdrawal of the drug.…”
Section: G Arb Sim S Scleroderma With Bullous Lesionsmentioning
confidence: 87%
“…Exfoliative dermatitis: Organic arsenic, chloroquine (Granirer, 1958), phenothiazines, gold salts, streptomycin, sulphonamides, penicillin, phenytoin, phenylbutazone (Maberly and Greenhalgh, 1970), mercury.…”
Section: Toxicmentioning
confidence: 99%
“…by drug interaction). Such drugs include salicylates, phenylbutazone and chloral hydrate, which displace warfarin from serum albumin, and oral antibiotics which disturb endogenous production of Vitamin K by intestinal bacteria. Verrucous: Bromides and iodides. Exfoliative dermatitis: Organic arsenic, chloroquine (Granirer, 1958), phenothiazines, gold salts, streptomycin, sulphonamides, penicillin, phenytoin, phenylbutazone (Maberly and Greenhalgh, 1970), mercury.It is important to remember that any drug eruption may evolve into this condition if it is severe enough or if the drug is continued after the original eruption has begun. Mercury is little used now but some ointments prescribed still contain it.…”
Section: Toxicmentioning
confidence: 99%