Exercise And Dietary Weight Loss In Overweight And Obese Older Adults With Knee OA

Messier, Stephen P.; Brown, Ryan L.; Gutekunst, David J.; Davis, Cralen; Jolla, J

doi:10.1097/00005768-200505001-00291

Cited by 10 publications

(30 citation statements)

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“…Intensity achieved during strength training using free or limb weights or Theraband was commonly a 10-repetition maximum with varying numbers of sets27 31 34 53 or was at least moderate 30 72 74. Aerobic exercise training, achieved via walking or cycling programmes, ranged from low25 69 to moderate34 37 44 50 57 59 61 64 intensity.…”

Section: Resultsmentioning

confidence: 99%

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Exercise for osteoarthritis of the knee: a Cochrane systematic review

et al. 2015

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ObjectiveTo determine whether land-based therapeutic exercise is beneficial for people with knee osteoarthritis (OA) in terms of reduced joint pain or improved physical function and quality of life.MethodsFive electronic databases were searched, up until May 2013. Randomised clinical trials comparing some form of land-based therapeutic exercise with a non-exercise control were selected. Three teams of two review authors independently extracted data and assessed risk of bias for each study. Standardised mean differences immediately after treatment and 2–6 months after cessation of formal treatment were separately pooled using a random effects model.ResultsIn total, 54 studies were identified. Overall, 19 (35%) studies reported adequate random sequence generation, allocation concealment and adequately accounted for incomplete outcome data. However, research results may be vulnerable to selection, attrition and detection bias. Pooled results from 44 trials indicated that exercise significantly reduced pain (12 points/100; 95% CI 10 to 15) and improved physical function (10 points/100; 95% CI 8 to 13) to a moderate degree immediately after treatment, while evidence from 13 studies revealed that exercise significantly improved quality of life immediately after treatment with small effect (4 points/100; 95% CI 2 to 5). In addition, 12 studies provided 2-month to 6-month post-treatment sustainability data which showed significantly reduced knee pain (6 points/100; 95% CI 3 to 9) and 10 studies which showed improved physical function (3 points/100; 95% CI 1 to 5).ConclusionsAmong people with knee osteoarthritis, land-based therapeutic exercise provides short-term benefit that is sustained for at least 2–6 months after cessation of formal treatment.

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Section: Resultsmentioning

confidence: 99%

“…According to the methodological quality assessment, a total of 19 of 54 studies (35%) could be considered as achieving ‘low risk of bias’ from the published report 22 24 26 34 35 37 38 48 52–55 57 62 70 71 73 74. Only 4 of the 54 included studies claimed blinding of study participants 26 31 36 62…”

Section: Resultsmentioning

confidence: 99%

Exercise for osteoarthritis of the knee: a Cochrane systematic review

et al. 2015

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“…It is reasonable to suggest that weight loss will lead to improvements in function, with a lowering of inflammatory markers. In previous research, it was found that mild weight loss (∼5% from baseline) using diet changes alone or a combination of diet and exercise interventions resulted in improvements in function in older obese and overweight adults with knee OA over 18 months 17 . In this same cohort, the dietary‐induced weight‐loss intervention produced significant reductions in CRP, IL‐6, and sTNFR1 18 .…”

mentioning

confidence: 76%

Inflammatory Biomarkers and Physical Function in Older, Obese Adults with Knee Pain and Self‐Reported Osteoarthritis After Intensive Weight‐Loss Therapy

Miller

Nicklas

Loeser

2008

J American Geriatrics Society

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“…A single blind, randomized controlled clinical trial conducted by Messier and colleagues [20] examining the effects of exercise and diet on weight loss among overweight and obese adults over age 60 years (mean age of 69 years) found that the combination intervention with both exercise and diet had significant weight loss, improvement in mobility (6 min walk distance and the stair-climb time) and 30.3% decreased in pain. The study did not include, however, the oldest old, cognitively impaired or functionally impaired people.…”

Section: Exercisementioning

confidence: 99%

Individualizing recommendations for weight management in the elderly

Chau

Cho

Jani

et al. 2008

Current Opinion in Clinical Nutrition and Metabolic Care

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The growing prevalence of obesity in the elderly population is becoming a major health problem and can affect functional status, can contribute to frailty and decline in activity, as well as worsening co-morbid medical problems. Practical recommendations for weight management in the elderly are challenging because of the obesity paradox in the elderly, and the lack of substantial research in this population. Individualized recommendations should be considered for elderly patients with a focus on the underlying medical problems, functional status and living environments.

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Exercise And Dietary Weight Loss In Overweight And Obese Older Adults With Knee OA

Cited by 10 publications

References 0 publications

Exercise for osteoarthritis of the knee: a Cochrane systematic review

Exercise for osteoarthritis of the knee: a Cochrane systematic review

Inflammatory Biomarkers and Physical Function in Older, Obese Adults with Knee Pain and Self‐Reported Osteoarthritis After Intensive Weight‐Loss Therapy

Individualizing recommendations for weight management in the elderly

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