Executive Dysfunction in Alzheimer Disease

Abstract

These findings support the assessment of executive function in persons with AD and the importance of frontal lobe dysfunction in AD.

Effects of kidney function, serum albumin and hemoglobin on dementia severity in the oldest old people with newly diagnosed Alzheimer’s disease in a residential aged care facility: a cross-sectional study

“…This finding was compatible with several previous reports that cognitive decline affects the performance of activities of daily living in patients with dementia [43]. Executive dysfunction is a common manifestation of AD in all stages, and it has been shown in several studies that there is a link between executive dysfunction and impaired performance on ADL scales [44]. The effect of cognitive functions on changes of daily functions is important because it will tell clinicians and families to provide appropriate interventions to improve or maintain daily performances for preparation of sufficient supporting resources in the care of older patients with dementia.…”

Effects of kidney function, serum albumin and hemoglobin on dementia severity in the oldest old people with newly diagnosed Alzheimer’s disease in a residential aged care facility: a cross-sectional study

“…This finding was compatible with several previous reports that cognitive decline affects the performance of activities of daily living in patients with dementia [43]. Executive dysfunction is a common manifestation of AD in all stages, and it has been shown in several studies that there is a link between executive dysfunction and impaired performance on ADL scales [44]. The effect of cognitive functions on changes of daily functions is important because it will tell clinicians and families to provide appropriate interventions to improve or maintain daily performances for preparation of sufficient supporting resources in the care of older patients with dementia.…”

Comparison of Prefrontal Atrophy and Episodic Memory Performance in Dysexecutive Alzheimer’s Disease and Behavioral-Variant Frontotemporal Dementia

“…On a cognitive level, our findings are consistent with a number of studies that have identified significant executive deficits in a subgroup of AD patients, using specific tests of executive function [2–4 , 51]. In keeping with previous studies [10–12 , 37], episodic memory performance was similarly impaired in both AD and bvFTD.…”

Impact of Executive Dysfunction on Verbal Memory Performance in Patients with Alzheimer's Disease

“…Using the criteria detailed in the Methods section in order to group AD patients based on executive performance revealed that 37% of the patients were classified into the IEF group. This percentage falls within previously reported ranges of proportions of IEF patients with AD using similar methodology (28% [5] to 64% [7]). SEF and IEF patients did not differ significantly on their age, gender, or dementia severity (neither by transformed score nor by the sum of boxes on the CDR).…”

Effects of kidney function, serum albumin and hemoglobin on dementia severity in the oldest old people with newly diagnosed Alzheimer’s disease in a residential aged care facility: a cross-sectional study

“…This finding was compatible with several previous reports that cognitive decline affects the performance of activities of daily living in patients with dementia [43]. Executive dysfunction is a common manifestation of AD in all stages, and it has been shown in several studies that there is a link between executive dysfunction and impaired performance on ADL scales [44]. The effect of cognitive functions on changes of daily functions is important because it will tell clinicians and families to provide appropriate interventions to improve or maintain daily performances for preparation of sufficient supporting resources in the care of older patients with dementia.…”

Comparison of Prefrontal Atrophy and Episodic Memory Performance in Dysexecutive Alzheimer’s Disease and Behavioral-Variant Frontotemporal Dementia

“…On a cognitive level, our findings are consistent with a number of studies that have identified significant executive deficits in a subgroup of AD patients, using specific tests of executive function [2–4 , 51]. In keeping with previous studies [10–12 , 37], episodic memory performance was similarly impaired in both AD and bvFTD.…”

Impact of Executive Dysfunction on Verbal Memory Performance in Patients with Alzheimer's Disease

“…Using the criteria detailed in the Methods section in order to group AD patients based on executive performance revealed that 37% of the patients were classified into the IEF group. This percentage falls within previously reported ranges of proportions of IEF patients with AD using similar methodology (28% [5] to 64% [7]). SEF and IEF patients did not differ significantly on their age, gender, or dementia severity (neither by transformed score nor by the sum of boxes on the CDR).…”

Effects of kidney function, serum albumin and hemoglobin on dementia severity in the oldest old people with newly diagnosed Alzheimer’s disease in a residential aged care facility: a cross-sectional study

“…This finding was compatible with several previous reports that cognitive decline affects the performance of activities of daily living in patients with dementia [43]. Executive dysfunction is a common manifestation of AD in all stages, and it has been shown in several studies that there is a link between executive dysfunction and impaired performance on ADL scales [44]. The effect of cognitive functions on changes of daily functions is important because it will tell clinicians and families to provide appropriate interventions to improve or maintain daily performances for preparation of sufficient supporting resources in the care of older patients with dementia.…”

Comparison of Prefrontal Atrophy and Episodic Memory Performance in Dysexecutive Alzheimer’s Disease and Behavioral-Variant Frontotemporal Dementia

“…On a cognitive level, our findings are consistent with a number of studies that have identified significant executive deficits in a subgroup of AD patients, using specific tests of executive function [2–4 , 51]. In keeping with previous studies [10–12 , 37], episodic memory performance was similarly impaired in both AD and bvFTD.…”

Impact of Executive Dysfunction on Verbal Memory Performance in Patients with Alzheimer's Disease

“…Using the criteria detailed in the Methods section in order to group AD patients based on executive performance revealed that 37% of the patients were classified into the IEF group. This percentage falls within previously reported ranges of proportions of IEF patients with AD using similar methodology (28% [5] to 64% [7]). SEF and IEF patients did not differ significantly on their age, gender, or dementia severity (neither by transformed score nor by the sum of boxes on the CDR).…”