Excitatory phenomena following the use of propofol in dogs

Effect of remifentanil on requirements for propofol administered by use of a target-controlled infusion system for maintaining anesthesia in dogs

“…26,27 Signs include muscle twitching, paddling, and limb rigidity with opisthotonus; some signs persist into the recovery period. 26,27 Signs include muscle twitching, paddling, and limb rigidity with opisthotonus; some signs persist into the recovery period.…”

Target-controlled infusion of propofol combined with variable rate infusion of remifentanil for anaesthesia of a dog with patent ductus arteriosus

“…1994). Excitatory phenomena following the administration of propofol in dogs are well recognized (Davies 1991; Smith et al. 1993).…”

Quantitative electroencephalographic findings in beagles anaesthetized with propofol

“…In veterinary medicine, propofol has been used successfully to control seizures occurring after surgical treatment of portosystemic shunts in dogs and cats (Heldman et al, 1999) and refractory seizures of intracranial origin (Steffen and Grasmuek, 2000). Dystonic movements in dogs following propofol anaesthesia have been described (Smedile et al, 1996;Davies, 1991). Both activation of the EEG and burst suppression have been reported in human patients affected by epilepsy under propofol anaesthesia at different dosage regimens (Smith et al, 1996).…”

“…Propofol anaesthesia is characterized by rapid onset, rapid hepatic metabolism, lack of accumulation on repeated administration, some respiratory depression, and a rapid and smooth recovery from anesthesia (Glen, 1980;Watkins et al, 1987), although neurological sequelae have been reported (Davies, 1991;Smedile The Veterinary Journal 166 (2003) [58][59][60][61][62][63][64][65][66] The Veterinary Journal www.elsevier.com/locate/tvjl et al, 1996). The cardiovascular depressant effects of propofol are well tolerated in healthy animals, but these effects must be considered carefully in patients with intrinsic cardiac disease.…”