Evolution in Trends of Primary Lower-Extremity Amputations Associated With Diabetes or Peripheral Artery Disease From 2006 to 2019

The Association Between Triglyceride-Glucose Index and Its Combination with Obesity Indicators and Lower Extremity Peripheral Artery Disease in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study

“…Only 10% display typical intermittent claudication symptoms, while 50% present with other lower limb symptoms, and the remaining 40% are asymptomatic. 9–11 Diabetic LEAD frequently coexists with diabetic peripheral neuropathy, where some patients exhibit diminished pain perception, obscuring the symptoms and severity of LEAD. Consequently, diabetic LEAD shows a higher prevalence of asymptomatic or atypical symptoms compared to non-diabetic LEAD.…”