Evidence of Influenza A Virus Infection in Cynomolgus Macaques, Thailand

Paungpin, Weena; Thongdee, Metawee; Ketchim, Natthaphat; Chaiwattanarungruengpaisan, Somjit; Saechin, Aeknarin; Sariya, Ladawan; Kaewchot, Supakarn; Puthavathana, Pilaipan; Wiriyarat, Witthawat

doi:10.3390/vetsci9030132

Cited by 3 publications

(3 citation statements)

References 29 publications

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“…Under experimental conditions, NHPs are used as models to study IAV infection, pathogenesis, and immunology [313,314]. However, a number of NHPs have been infected with hIAV under natural conditions in different Asian countries [315][316][317]. Likewise, baboons in Kenya have been infected with human-like H1 and H3 viruses, most likely due to human-to-animal transmission [318].…”

Section: Non-human Primates (Nhps)mentioning

confidence: 99%

Zoonotic Animal Influenza Virus and Potential Mixing Vessel Hosts

Abdelwhab

Mettenleiter

2023

Viruses

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Influenza viruses belong to the family Orthomyxoviridae with a negative-sense, single-stranded segmented RNA genome. They infect a wide range of animals, including humans. From 1918 to 2009, there were four influenza pandemics, which caused millions of casualties. Frequent spillover of animal influenza viruses to humans with or without intermediate hosts poses a serious zoonotic and pandemic threat. The current SARS-CoV-2 pandemic overshadowed the high risk raised by animal influenza viruses, but highlighted the role of wildlife as a reservoir for pandemic viruses. In this review, we summarize the occurrence of animal influenza virus in humans and describe potential mixing vessel or intermediate hosts for zoonotic influenza viruses. While several animal influenza viruses possess a high zoonotic risk (e.g., avian and swine influenza viruses), others are of low to negligible zoonotic potential (e.g., equine, canine, bat and bovine influenza viruses). Transmission can occur directly from animals, particularly poultry and swine, to humans or through reassortant viruses in “mixing vessel” hosts. To date, there are less than 3000 confirmed human infections with avian-origin viruses and less than 7000 subclinical infections documented. Likewise, only a few hundreds of confirmed human cases caused by swine influenza viruses have been reported. Pigs are the historic mixing vessel host for the generation of zoonotic influenza viruses due to the expression of both avian-type and human-type receptors. Nevertheless, there are a number of hosts which carry both types of receptors and can act as a potential mixing vessel host. High vigilance is warranted to prevent the next pandemic caused by animal influenza viruses.

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Section: Non-human Primates (Nhps)mentioning

confidence: 99%

Zoonotic Animal Influenza Virus and Potential Mixing Vessel Hosts

Abdelwhab

Mettenleiter

2023

Viruses

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“…The Macaques are reported to harbor and transmit specific zoonotic pathogens. These disease includes malaria, tuberculosis, influenza A and B, Simian Foamy Virus (SFV), and Macacine Herpesvirus 1 (MaHV1/B virus) [ 7 , 8 , 9 ]. The direct effect of long-tailed macaque overpopulation is a lack of psychosocial well-being and discomfort for tourists as well as losses for farmers due to the cost of crop guarding [ 10 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Long-Tailed Macaque (Macaca fascicularis) Contraception Methods: A Systematic Review

Mikail

Azizan

Noor

et al. 2023

Biology

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The contraception-based approach to wildlife management is a humane and effective alternative to population control methods. Wildlife management only has a few conventional ways to control overpopulation, such as culling, translocation, poisoning, and allowing natural death. Nevertheless, these methods usually have short-term, lethal, and unethical effects. The present systematic review aims to review the knowledge on contraception reported in long-tailed macaques as an alternative to population control. We obtained 719 records from searching CABI, PubMed, ScienceDirect, and Scopus electronic databases. After the screening and selection process, according to PRISMA guidelines, 19 articles that met the eligibility criteria were chosen. Of the 19 articles, 15 were studies on female long-tailed macaque contraception methods (six (6) hormonal and nine (9) non-hormonal). We analyzed four (4) selected articles on male Cynomolgus monkey contraception methods (two (2) hormonal and two (2) non-hormonal). One of the nine (9) articles on female long-tailed macaque contraception reports negative results. Furthermore, only two (2) studies used free-ranging long-tailed macaques as test subjects, while seventeen (17) tested on captive ones. The challenges of long-tailed macaque contraception identified in this review were the effectiveness of the contraceptive, the administration route, the economic feasibility, the distinction between captive and free-ranging Cynomolgus macaques, the choice of permanent or reversible contraception, the capability of contraceptive use for population control, and the lack of studies on the free-ranging long-tailed macaque. Notwithstanding the literature gap on long-tailed macaque contraception for population control, long-tailed macaque contraception exhibits potential as an alternative method to culling long-tailed macaque. Future research should address these obstacles to support the long-tailed macaque contraception as an alternative population control method.

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“…A novel point of view on transmitting infectious diseases is presented by Koster et al [ 1 ] in a review of how human pathogens affect great apes. This perspective is reinforced by Paungpin et al [ 2 ], who discovered human influenza viruses in macaques in Thailand. The entrance of humans into wild environments for agriculture, forestry, and animal breeding leads to close contact with domestic and wild animals.…”

mentioning

confidence: 95%