Everyday psychological functioning in children with unilateral cerebral palsy: does executive functioning play a role?

Whittingham, Koa; Bodimeade, Harriet L; Lloyd, Owen; Boyd, Roslyn N.

doi:10.1111/dmcn.12374

Cited by 47 publications

(30 citation statements)

References 37 publications

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“…Studies that have focused on executive functions have reported difficulties with inhibitory control, shifting and categorization (Bottcher, 2010, Christ et al, 2003, Jenks et al, 2009, Kolk and Talvik, 2000) which can explain difficulties in everyday life (Whittingham et al, 2014). Lesions of the basal ganglia and thalamic systems may impair focused attention and executive function (Bottcher, 2010).…”

Section: Introductionmentioning

confidence: 99%

White matter integrity in dyskinetic cerebral palsy: Relationship with intelligence quotient and executive function

Laporta-Hoyos

Pannek

Ballester‐Plané

et al. 2017

NeuroImage: Clinical

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BackgroundDyskinetic cerebral palsy (CP) is one of the most disabling motor types of CP and has been classically associated with injury to the basal ganglia and thalamus. Although cognitive dysfunction is common in CP, there is a paucity of published quantitative analyses investigating the relationship between white matter (WM) microstructure and cognition in this CP type.AimsThis study aims (1) to compare brain WM microstructure between people with dyskinetic CP and healthy controls, (2) to identify brain regions where WM microstructure is related to intelligence and (3) to identify brain regions where WM microstructure is related to executive function in people with dyskinetic CP and (4) to identify brain regions where the correlations are different between controls and people with CP in IQ and executive functions.Patients and methodsThirty-three participants with dyskinetic CP (mean ± SD age: 24.42 ± 12.61, 15 female) were age and sex matched with 33 controls. Participants underwent a comprehensive neuropsychological battery to assess intelligence quotient (IQ) and four executive function domains (attentional control, cognitive flexibility, goal setting and information processing). Diffusion weighted MRI scans were acquired at 3T. Voxel-based whole brain groupwise analyses were used to compare fractional anisotropy (FA) and of the CP group to the matched controls using a general lineal model. Further general linear models were used to identify regions where white matter FA correlated with IQ and each of the executive function domains.ResultsWhite matter FA was significantly reduced in the CP group in all cerebral lobes, predominantly in regions connected with the parietal and to a lesser extent the temporal lobes. There was no significant correlation between IQ or any of the four executive function domains and WM microstructure in the control group. In participants with CP, lower IQ was associated with lower FA in all cerebral lobes, predominantly in locations that also showed reduced FA compared to controls. Attentional control, goal setting and information processing did not correlate with WM microstructure in the CP group. Cognitive flexibility was associated with FA in regions known to contain connections with the frontal lobe (such as the superior longitudinal fasciculus and cingulum) as well as regions not known to contain tracts directly connected with the frontal lobe (such as the posterior corona radiata, posterior thalamic radiation, retrolenticular part of internal capsule, tapetum, body and splenium of corpus callosum).ConclusionThe widespread loss in the integrity of WM tissue is mainly located in the parietal lobe and related to IQ in dyskinetic CP. Unexpectedly, executive functions are only related with WM microstructure in regions containing fronto-cortical and posterior cortico-subcortical pathways, and not being specifically related to the state of fronto-striatal pathways which might be due to brain reorganization. Further studies of this nature may improve our understanding of the neurobiol...

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Section: Introductionmentioning

confidence: 99%

White matter integrity in dyskinetic cerebral palsy: Relationship with intelligence quotient and executive function

Laporta-Hoyos

Pannek

Ballester‐Plané

et al. 2017

NeuroImage: Clinical

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“…Compared with able-bodied students, adolescents with PD showed no significant differences in prosocial behavior in some studies (Whittingham et al 2014;Yeates et al 2013) and lower levels of prosocial behavior in others (Brossard-Racine et al 2012).…”

Section: Peculiarities Of the Attainment Of Developmental Tasks In Admentioning

confidence: 81%

Perceived Attainment of Developmental Tasks in Adolescents with and without Physical Disabilities

Behle

Pinquart

2015

J Dev Phys Disabil

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The present study explored whether adolescents with (N = 183) and without (N = 320) physical disabilities (PD) differed in their perceived attainment of 12 agetypical developmental tasks. We were also interested in whether the success varied according to the extent of motoric restriction. The groups differed in the perceived attainment of three out of 12 tasks. Adolescents with physical impairments perceived lower levels of success than their peers without PD with regard to peer-group integration, but higher levels of success in gaining academic competence and autonomy from parents. Their higher perceived autonomy was explained by the fact that many students with disabilities did not live with their parents during the school term. Higher severity of disability was associated with lower perceived attainment in five developmental tasks (autonomy development, development of realistic self-perception, development of romantic relationships, gender-role awareness, sociopolitical awareness). The results indicate that many young people with a PD, and those with low physical restrictions in particular, demonstrate substantial resilience and are as successful as their peers without disabilities in accomplishing their developmental tasks. Interventions aimed at promoting the attainment of developmental tasks are recommended for adolescents with severe disabilities.A physical disability (PD) can be defined as a condition where a person experiences significant deviation or loss in their body function or structure that results in limitations in physical activity (World Health Organization 2001). According to official statistics, 0.3 % of German school students were classified as having a PD in 2012 with 74 % of J Dev Phys Disabil (2015) 27:773-787

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“…Studies have shown that persons with congenital disabilities such as cerebral palsy (CP) and spina bifida (SB), even if they have fairly good motor function and no intellectual disability, often have difficulties when performing everyday activities, as a result of executive dysfunction. This can involve difficulties with planning, initiation and problem solving [6][7][8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

“With CO-OP I’m the boss” – experiences of the cognitive orientation to daily occupational performance approach as reported by young adults with cerebral palsy or spina bifida

Öhrvall

Bergqvist

Hofgren

et al. 2019

Disability and Rehabilitation

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Everyday psychological functioning in children with unilateral cerebral palsy: does executive functioning play a role?

Cited by 47 publications

References 37 publications

White matter integrity in dyskinetic cerebral palsy: Relationship with intelligence quotient and executive function

White matter integrity in dyskinetic cerebral palsy: Relationship with intelligence quotient and executive function

Perceived Attainment of Developmental Tasks in Adolescents with and without Physical Disabilities

“With CO-OP I’m the boss” – experiences of the cognitive orientation to daily occupational performance approach as reported by young adults with cerebral palsy or spina bifida

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