Event-Related Potential P300 in Multiple Sclerosis

P300 Wave Changes in Patients with Multiple Sclerosis

“…Giesser et al (26) could demonstrate a high correlation between P300 latencies and cognitive functions typically impaired in MS such as visual and verbal memory and storage and retrieval strategies. In several other studies as well, the increase of P300 latency was significantly correlated with both the cognitive impairment and the degree of white matter involvement revealed by MRI (12, 13, 27). …”

“…The importance of evaluation of the P300 in patients with MS in diagnosis of cognitive dysfunction is shown in many studies (12, 13, 19, 26, 27). Giesser et al (26) could demonstrate a high correlation between P300 latencies and cognitive functions typically impaired in MS such as visual and verbal memory and storage and retrieval strategies.…”

P300 Wave Changes in Patients with Multiple Sclerosis

“…Giesser et al (26) could demonstrate a high correlation between P300 latencies and cognitive functions typically impaired in MS such as visual and verbal memory and storage and retrieval strategies. In several other studies as well, the increase of P300 latency was significantly correlated with both the cognitive impairment and the degree of white matter involvement revealed by MRI (12, 13, 27). …”

“…The importance of evaluation of the P300 in patients with MS in diagnosis of cognitive dysfunction is shown in many studies (12, 13, 19, 26, 27). Giesser et al (26) could demonstrate a high correlation between P300 latencies and cognitive functions typically impaired in MS such as visual and verbal memory and storage and retrieval strategies.…”

Relationships between the resting-state network and the P3: Evidence from a scalp EEG study

“…Constructed networks containing these regions have been found to be correlated with higher-order cognitive processes, such as attention, intelligence, and working memory, and simultaneous interactions between these regions contribute to the P3 4 39 . People with cognitive deficits due to mental and neurological diseases showed longer P3 latencies and smaller P3 amplitudes 40 . Lesions to the grey and white matter of the frontal and temporo-parietal junction due to hazardous substances resulted in P3 amplitude abnormalities 17 18 .…”

Cognitive Event-Related Potentials–The P300 Wave Is a Prognostic Factor of Long-Term Disability Progression in Patients With Multiple Sclerosis

“…1,8–13 Ellger et al 14 found longer P300 latencies in secondary progressive MS. P300 latency is related to attention and memory deficit, 8–10,15 a higher Expanded Disability Status Scale (EDSS) score, 4,5,11,14,15 disease duration, 8,9,15,16 and MRI lesion burden. 8,10,13,17 In our previous study on a group of 110 patients with MS, auditory P300 latency was prolonged in 69% of patients compared with the 130 healthy controls. P300 latency correlated with the patients' cognitive dysfunction and their quality of life.…”

“…The relationships between P300 data and neurophysiologic tests, clinical variables, and MRI data has been described. 1,[8][9][10][11][12][13] Ellger et al 14 found longer P300 latencies in secondary progressive MS. P300 latency is related to attention and memory deficit, [8][9][10]15 a higher Expanded Disability Status Scale (EDSS) score, 4,5,11,14,15 disease duration, 8,9,15,16 and MRI lesion burden. 8,10,13,17 In our previous study on a group of 110 patients with MS, auditory P300 latency was prolonged in 69% of patients compared with the 130 healthy controls.…”

P300 Wave Changes in Patients with Multiple Sclerosis

“…Giesser et al (26) could demonstrate a high correlation between P300 latencies and cognitive functions typically impaired in MS such as visual and verbal memory and storage and retrieval strategies. In several other studies as well, the increase of P300 latency was significantly correlated with both the cognitive impairment and the degree of white matter involvement revealed by MRI (12, 13, 27). …”

“…The importance of evaluation of the P300 in patients with MS in diagnosis of cognitive dysfunction is shown in many studies (12, 13, 19, 26, 27). Giesser et al (26) could demonstrate a high correlation between P300 latencies and cognitive functions typically impaired in MS such as visual and verbal memory and storage and retrieval strategies.…”

Relationships between the resting-state network and the P3: Evidence from a scalp EEG study

“…Constructed networks containing these regions have been found to be correlated with higher-order cognitive processes, such as attention, intelligence, and working memory, and simultaneous interactions between these regions contribute to the P3 4 39 . People with cognitive deficits due to mental and neurological diseases showed longer P3 latencies and smaller P3 amplitudes 40 . Lesions to the grey and white matter of the frontal and temporo-parietal junction due to hazardous substances resulted in P3 amplitude abnormalities 17 18 .…”

Cognitive Event-Related Potentials–The P300 Wave Is a Prognostic Factor of Long-Term Disability Progression in Patients With Multiple Sclerosis

“…1,8–13 Ellger et al 14 found longer P300 latencies in secondary progressive MS. P300 latency is related to attention and memory deficit, 8–10,15 a higher Expanded Disability Status Scale (EDSS) score, 4,5,11,14,15 disease duration, 8,9,15,16 and MRI lesion burden. 8,10,13,17 In our previous study on a group of 110 patients with MS, auditory P300 latency was prolonged in 69% of patients compared with the 130 healthy controls. P300 latency correlated with the patients' cognitive dysfunction and their quality of life.…”

“…The relationships between P300 data and neurophysiologic tests, clinical variables, and MRI data has been described. 1,[8][9][10][11][12][13] Ellger et al 14 found longer P300 latencies in secondary progressive MS. P300 latency is related to attention and memory deficit, [8][9][10]15 a higher Expanded Disability Status Scale (EDSS) score, 4,5,11,14,15 disease duration, 8,9,15,16 and MRI lesion burden. 8,10,13,17 In our previous study on a group of 110 patients with MS, auditory P300 latency was prolonged in 69% of patients compared with the 130 healthy controls.…”

P300 Wave Changes in Patients with Multiple Sclerosis

“…Giesser et al (26) could demonstrate a high correlation between P300 latencies and cognitive functions typically impaired in MS such as visual and verbal memory and storage and retrieval strategies. In several other studies as well, the increase of P300 latency was significantly correlated with both the cognitive impairment and the degree of white matter involvement revealed by MRI (12, 13, 27). …”

“…The importance of evaluation of the P300 in patients with MS in diagnosis of cognitive dysfunction is shown in many studies (12, 13, 19, 26, 27). Giesser et al (26) could demonstrate a high correlation between P300 latencies and cognitive functions typically impaired in MS such as visual and verbal memory and storage and retrieval strategies.…”

Relationships between the resting-state network and the P3: Evidence from a scalp EEG study

“…Constructed networks containing these regions have been found to be correlated with higher-order cognitive processes, such as attention, intelligence, and working memory, and simultaneous interactions between these regions contribute to the P3 4 39 . People with cognitive deficits due to mental and neurological diseases showed longer P3 latencies and smaller P3 amplitudes 40 . Lesions to the grey and white matter of the frontal and temporo-parietal junction due to hazardous substances resulted in P3 amplitude abnormalities 17 18 .…”

Cognitive Event-Related Potentials–The P300 Wave Is a Prognostic Factor of Long-Term Disability Progression in Patients With Multiple Sclerosis

“…1,8–13 Ellger et al 14 found longer P300 latencies in secondary progressive MS. P300 latency is related to attention and memory deficit, 8–10,15 a higher Expanded Disability Status Scale (EDSS) score, 4,5,11,14,15 disease duration, 8,9,15,16 and MRI lesion burden. 8,10,13,17 In our previous study on a group of 110 patients with MS, auditory P300 latency was prolonged in 69% of patients compared with the 130 healthy controls. P300 latency correlated with the patients' cognitive dysfunction and their quality of life.…”

“…The relationships between P300 data and neurophysiologic tests, clinical variables, and MRI data has been described. 1,[8][9][10][11][12][13] Ellger et al 14 found longer P300 latencies in secondary progressive MS. P300 latency is related to attention and memory deficit, [8][9][10]15 a higher Expanded Disability Status Scale (EDSS) score, 4,5,11,14,15 disease duration, 8,9,15,16 and MRI lesion burden. 8,10,13,17 In our previous study on a group of 110 patients with MS, auditory P300 latency was prolonged in 69% of patients compared with the 130 healthy controls.…”