Purpose: The aim of this study was to assess the validity and reliability of the Chinese version of mental vulnerability questionnaire (MVQ) for undergraduate students.Design and Methods: A cross-sectional design was conducted in a sample of 1217 undergraduate students.Findings: The Cronbach's α of the overall scale was 0.901, the split-half reliability coefficient was 0.742, and the test-retest reliability coefficient was 0.935. Three-factors model was got by using exploratory factor analysis, the communalities of the items were 0.646 to 0.848, explaining 75.736% variance. With confirmatory factor analysis the fit indices were chi-square/degree of freedom (CMIN/DF) = 2.796, comparative fit index (CFI) = 0947, GFI = 0.920, adjustedgoodness of fit index (AGFI) = 0.902, incremental fit index (IFI) = 0.947, root mean squareerror of approximation (RMSEA) = 0.055, Tucker Lewis index (TLI) = 0.940, root mean residual (RMR) = 0.051.