Evaluation of the hemodynamics and right ventricular function in pulmonary hypertension by echocardiography compared with right-sided heart catheterization

Abstract

The present study aimed to evaluate hemodynamics and right ventricular function in patients with pulmonary hypertension (PH) using transthoracic echocardiography and to compare these results with measurements obtained using right-sided heart catheterization (RHC). A total of 75 patients with PH were examined using echocardiography and RHC. Patients were divided into the following two groups according to their difference between SPAPecho and SPAPRHC measurement: The overestimated group and underestimated group. The overestimated group included the subgroups groupover-A (difference <20 mmHg) and groupover-B (difference ≥20 mmHg), and the underestimated group included groupunder-A (absolute value of the difference <20 mmHg) and groupunder-B (absolute value of the difference ≥20 mmHg). SPAPecho measurements were revealed to be significantly positively correlated with SPAPRHC measurements (r=0.794; P<0.01). Among all echocardiographic measurements, only tricuspid annular plane systolic excursion (TAPSE) was significantly different between groups; it was increased in groupover-A and groupunder-A compared with groupover-B (P<0.01). Although SPAP measurements obtained using echocardiography were significantly positively correlated with those obtained using RHC, a high proportion of overestimation or underestimation of SPAP by echocardiography remained.

The accuracy and influencing factors of Doppler echocardiography in estimating pulmonary artery systolic pressure: comparison with right heart catheterization: a retrospective cross-sectional study

“…As the most well-adopted approach in PH screening, sPAP ECHO has also been shown to be a reliable method [ 3 ]; however, it has not yet been examined whether sPAP ECHO is superior to other parameters in determining the probability of PH. sPAP ECHO can also provide valuable information for evaluating treatment response and even predicting prognosis [ 4 , 5 ]; however, there is still a high proportion of overestimation or underestimation of sPAP ECHO [ 6 ]. To evaluate PH patients’ condition appropriately and avoid too invasive examination, we need to understand situations in which sPAP ECHO is under/overestimated.…”

Accuracy and Influencing factors of Pulmonary Artery Systolic Pressure estimated by Doppler Echocardiography: Comparsion with Right Heart Catheterization

“…Besides, sPAP ECHO can also provide valuable information in evaluating treatment response and even predicting prognosis [2,3] . But high proportion of overestimation or underestimation of sPAP ECHO still remained [4] . As previous studies showed, TR severity, TR signal quality, the level of pulmonary artery systolic pressure and right ventricular function would affect the accuracy of sPAP ECHO [5][6][7] .…”

A better method to evaluate the reliability of echocardiography for assessment of pulmonary hypertension: comparison of tricuspid regurgitant spectrum quality grading and tricuspid valve regurgitation degree

“…Especially for the latter, the volume of tricuspid regurgitation (TR), the operator’s measurement technique [e.g., taking multiple views to obtain the optimal window, ensuring the maximal continuous-wave (CW) Doppler velocity to flow angle is correctly aligned ( 19 ) and avoiding eccentric jets ( 6 ), over-gaining and artifacts ( 20 ), etc. ], and the patient’s own conditions [e.g., age, sex, body mass index (BMI), breathing, heart rate, cardiopulmonary and metabolic comorbidities, and the ability to change position during examination ( 1 , 21 - 24 ), etc.] all influence the sharpness of the spectral image.…”