Evaluation of the Global Lung Initiative 2012 Reference Values for Spirometry in African Children

Arigliani, Michele; Canciani, Mario; Mottini, Giovanni; Altomare, Michele; Magnolato, Andrea; Clemente, Sofia; Tshilolo, Léon; Cogo, Paola; Quanjer, Philip H.

doi:10.1164/rccm.201604-0693oc

Cited by 54 publications

(59 citation statements)

References 43 publications

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“…In a Kenyan study, stunting was associated with tachypnoea among HIV-infected adolescents [9*]. Stunting is a marker of delayed somatic growth; therefore, stunted children are likely to have smaller lungs [77*], which may subsequently predispose to CLD.…”

Section: Risk Factors For Hiv-associated Chronic Lung Disease Among Amentioning

confidence: 99%

Bronchiectasis and other chronic lung diseases in adolescents living with HIV

Attia

Miller

Ferrand

2017

Current Opinion in Infectious Diseases

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Purpose of review The incidence of pulmonary infections has declined dramatically with improved access to antiretroviral therapy (ART) and co-trimoxazole prophylaxis, but chronic lung disease (CLD) is an increasingly recognized but poorly understood complication in adolescents with perinatally-acquired HIV. Recent findings There is a high prevalence of chronic respiratory symptoms, abnormal spirometry and chest radiographic abnormalities among HIV-infected adolescents in sub-Saharan Africa, where 90% of the world’s HIV-infected children live. The incidence of lymphocytic interstitial pneumonitis, the most common cause of CLD in the pre-ART era, has declined with increased ART access. Small airways disease, particularly constrictive obliterative bronchiolitis and bronchiectasis are emerging as leading causes of CLD among HIV-infected adolescents in low- and middle-income countries. Asthma may be more common in high-income settings. Likely risk factors for CLD include recurrent pulmonary infections, air pollution, HIV-related immune dysfunction and untreated HIV infection, particularly during critical stages of lung development. Summary Globally, the importance of HIV-associated CLD as a cause of morbidity and mortality is increasing, especially as survival has improved dramatically with ART and growing numbers of children living with HIV enter adolescence. Further research is urgently needed to elucidate the natural history and pathogenesis of CLD, and to determine optimal screening, diagnostic and treatment strategies.

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Section: Risk Factors For Hiv-associated Chronic Lung Disease Among Amentioning

confidence: 99%

Bronchiectasis and other chronic lung diseases in adolescents living with HIV

Attia

Miller

Ferrand

2017

Current Opinion in Infectious Diseases

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“…The ERS/GLI 2012 reference values have been evaluated in several populations and has appeared to be appropriate for Australasian aged 4–80 years, all ages Norwegian, schoolchildren in sub‐Saharan Africa, German elderly women, Polish children and British children but not for Tunisian adults, white Brazilian adults and Swedish adults . Although the ERS/GLI 2012 reference equations were also based on data from a Southeast Asian subpopulation ( n = 8255) represented by countries, such as Thailand, Taiwan and China, no study has independently evaluated the agreement between the ERS/GLI 2012 equations in an Asian population.…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies showed that lung function volumes in Asians and Africans are considerably lower than in Caucasians . The observed differences between reference equations may be explained by differences in population characteristics, although the study design used for each study population may also explain some of the variation .…”

Section: Introductionmentioning

confidence: 99%

“…20 Previous studies showed that lung function volumes in Asians and Africans are considerably lower than in Caucasians. 6,7,13 The observed differences between reference equations may be explained by differences in population characteristics, although the study design used for each study population may also explain some of the variation. 21,22 As the definition of obstructive and restrictive airway diseases relies heavily on spirometry, it is important that lung function equations used for pulmonary function are validated in the local setting.…”

Section: Introductionmentioning

confidence: 99%

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Global Lung Initiative 2012 spirometry reference values in a large Asian cohort of Malay, Chinese and Indian ancestry

et al. 2018

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“…Several studies have now shown that when a large representative sample of healthy individuals is obtained, and the American Thoracic Society/European Respiratory Society (ATS/ERS) technical standards for measurement and quality control are applied to the data, the overall pattern of lung growth and development described with the GLI equations are generalizable to many populations. The study by Blake et al .…”

mentioning

confidence: 99%