Evaluation of the Endotracheal Intubating Conditions of Rocuronium (ORG 9426) and Succinylcholine in Outpatient Surgery

Pühringer, F. K.; Khuenl-Brady, Karin S.; Koller, Johann; Mitterschiffthaler, G.

doi:10.1213/00000539-199207000-00007

Cited by 85 publications

(73 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2 and Sharma et al (1971). 3 In the present study, there was no significant difference as far as weight was concerned and it was in accordance with Puhringer FK et al (1995). 4 and Weinstein JA et al (1988).…”

Section: Discussionsupporting

confidence: 89%

Comparative Study of Pretreatment With Rocuronium and Vecuronium in Post Succinylcholine Fasciculation, Intubation Condition and Myalgia

S¹,

Kiran²,

G³

2016

jemds

View full text Add to dashboard Cite

Succinylcholine has quicker onset of action, reliable and excellent intubating conditions with shorter duration but has undesirable side effects as fasciculation, rise intraocular pressure, rise in intragastric pressure and subsequent vomiting and regurgitation hyperkalaemia, rise serum CPK levels, myalgia and myoglobinuria. It is contraindicated in anticipated difficult intubation, severe kidney and liver disease, trauma, pregnancy, etc. Many methods were tried to decrease these side effects of succinylcholine by many scientists. Pretreatment with non-depolarizing muscle relaxant is one of that which found to be successful. In the present study, Rocuronium and Vecuronium were tried to evaluate their efficacy in reducing post succinylcholine fasciculation, intubating conditions, serum potassium and CPK, myalgia and myoglobin; 150 patients were divided into three groups according to administration normal saline Rocuronium, Vecuronium as pretreatment before Succinylcholine where general anaesthesia administration was essential. It was observed that pretreatment with Rocuronium and Vecuronium significantly reduced incidence and severity of fasciculation, better intubating conditions, no change in serum potassium and CPK levels, reduction in Myalgia and no change in myoglobin postoperatively. Rocuronium was found to be better than Vecuronium in all respects to minimize side effects of Succinylcholine.

show abstract

Section: Discussionsupporting

confidence: 89%

Comparative Study of Pretreatment With Rocuronium and Vecuronium in Post Succinylcholine Fasciculation, Intubation Condition and Myalgia

S¹,

Kiran²,

G³

2016

jemds

View full text Add to dashboard Cite

show abstract

“…The present study was comparable with study of Penchalaiah C et al [13] Thus increasing the dose of rocuronium bromide from 0.6 mg/kg to 1mg/kg body weight increased the incidence of excellent intubating conditions. The study results were comparable to Toni Magorian et al, [14] Cooper et al [15] and Puhringer et al [16] and K. C. McCourt et al [17] …”

Section: Intubating Conditionssupporting

confidence: 86%

Comparative Study of Succinylcholine with Different Doses of Rocuronium Bromide for Tracheal Intubation during General Anaesthesia

Panda¹,

Padhihari²,

Meitei³

et al. 2017

IOSR JDMS

View full text Add to dashboard Cite

“…However Puhringer et al (1992) 7 observed clinically acceptable condition in 100% patients with excellent condition 85% after rocuronium 0.6mg/kg at 60 seconds. R. Cooper et al 1992, 2 also found clinically acceptable condition in more than 95% of the patients with excellent condition 65%.…”

Section: Side Effects Group I Group Ii Group Iii Group Ivmentioning

confidence: 97%

Comparative Evaluation of Intubat Ing Conditions After Succinylch O Line and Different Doses of Rocuoronium

Dwivedi¹,

Dwivedi²

2015

jemds

View full text Add to dashboard Cite

BACKGROUND:Succinylcholine is widely used to facilitate intubation but it is contraindicated and hazardous in some medical conditions and Rocuronium is safer alternative. Aim: To study the intubating conditions obtained after different doses of Rocuronium and to compare with succinylcholine. SETTING AND DESIGN: Randomized and prospective study. METHODS: 100 adult patients posted for major surgeries under general anaesthesia divided into four groups of 25 each depending on dose and muscle relaxant given. Intubating conditions were assessed using standard scoring system, results were tabulated and analysed. STATISTICAL ANALYSIS: Results were analysed using chi-square test and unpaired t test. RESULTS: Intubating conditions after Rocuronium 0.6 mg/kg body weight at 90 seconds and Rocuronium 0.9 mg/kg body weight at 60 seconds are clinically acceptable in 100% of the patients and are equivalent to succinylcholine 1.5 mg/kg BW. CONCLUSION: Rocuronium is alternative and safer choice of succinylcholine in the conditions where succinylcholine is contraindicated and hazardous.

show abstract

Evaluation of the Endotracheal Intubating Conditions of Rocuronium (ORG 9426) and Succinylcholine in Outpatient Surgery

Cited by 85 publications

References 0 publications

Comparative Study of Pretreatment With Rocuronium and Vecuronium in Post Succinylcholine Fasciculation, Intubation Condition and Myalgia

Comparative Study of Pretreatment With Rocuronium and Vecuronium in Post Succinylcholine Fasciculation, Intubation Condition and Myalgia

Comparative Study of Succinylcholine with Different Doses of Rocuronium Bromide for Tracheal Intubation during General Anaesthesia

Comparative Evaluation of Intubat Ing Conditions After Succinylch O Line and Different Doses of Rocuoronium

Contact Info

Product

Resources

About