Evaluation of the effect of honey on the healing of tooth extraction wounds in 4- to 9-year-old children

Mokhtari, Sepideh; Sanati, I; Abdolahy, Sh; Hosseini, Zahra

doi:10.4103/njcp.njcp_102_19

Cited by 12 publications

(6 citation statements)

References 2 publications

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“…However, recent studies have shown that measuring wound borders alone is sufficient for reporting wound healing, even if the depth of the wound is neglected ( Mokhtari et al, 2019 ), and the sample size limitation is a consequence of the COVID-19 pandemic.…”

Section: Discussionmentioning

confidence: 99%

“…Landry, Turnbull, and Howley index (LWHI) and H 2 O 2 epithelialisation tests were performed 2 weeks and 4 weeks after tooth extraction ( Ustaoğlu et al, 2020 ). In addition, the extraction socket was measured ( Mokhtari et al, 2019 ). The LWHI evaluates the extraction socket with regard to wound size, tissue colour, bleeding on palpation, presence of granulation tissue, presence of pus, and gingival margin status.…”

Section: Methodsmentioning

confidence: 99%

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Evaluation of post-extraction healing after atraumatic axial tooth extraction using Benex system II versus conventional extraction: Randomized control trial

Makki

Nassar

Alharbi

et al. 2021

The Saudi Dental Journal

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Background and Purpose Tooth extraction is critical for dental treatment complications. One of the most discussed topics is socket healing after extraction. The Benex system allows extraction without causing unnecessary socket expansion by removing the tooth vertically, preserving both bone and soft tissue. Aim To assess postoperative healing signs, symptoms, and complications using the Benex extraction system and compare it with conventional extraction among patients at Umm Al-Qura University. Methods Thirty-eight patients with hopeless single-rooted teeth were included. They were divided into two equal groups: one in which teeth were extracted using the conventional method and one in which extractions were performed by Benex. The Benex system for tooth extraction was performed by drilling into the root canal, followed by screw insertion. Once the extractor was properly positioned, extraction was accomplished by turning the hand screw clockwise. At baseline, the wound size was evaluated. On days 1, 3, and 7 after extraction, telephone interviews were conducted to evaluate pain and post-extraction complications using a pain scale and questionnaire. Socket healing and wound size were evaluated after 2 and 4 weeks of extraction using the healing index and H 2 O 2 epithelization test. Results The Benex extraction system accelerated early soft-tissue healing and decreased pain and wound size compared with the control group. Conclusion. The Benex system is relatively safe and easy to use, but this does not eliminate the need for a degree of education and training. Proper selection of the case, knowledge of using the device, and implementation of that knowledge in the treatment planning are important factors in ensuring success with this system.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Evaluation of post-extraction healing after atraumatic axial tooth extraction using Benex system II versus conventional extraction: Randomized control trial

Makki

Nassar

Alharbi

et al. 2021

The Saudi Dental Journal

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“…Healing socket consists of three new tissue components; epithelium, connective tissue, and bone tissue. Interactive dynamic changes take place between these 3 components during healing period (4) . The wound socket healing is influenced by various molecules, inflammation mediators, integrin the growth factors that act on vascularization, new bone formation, and finally reepithelization covering socket surface (5) .…”

Section: Introductionmentioning

confidence: 99%

Histological and Histomorphometric Evaluation of Socket Healing After Application of Epidermal Growth Factor with synthetic hydroxyapatite powder in Rats

K Al-khafaji

2023

MDJ

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Background: One of the serious challenges in dental treatment is socket healing after tooth extraction. Various researchers have attempted to develop efficient therapies for healing and regenerating damaged tissues after extraction. Many tissue engineering technologies have been used now a day to enhance tissue healing. Aim: The present study was planned to evaluate the efficacy of epidermal growth factor with synthetic hydroxyapatite powder in socket healing. Methods: six-Thirty male rats were included in this study and their lower incisors teeth were subjected to extraction. Animals were divided into the following three groups according to socket treatment. (A) control, socket hole left to heal without any application, (B)application of hydroxyapatite powder (HAP) in the socket, (C) application of epidermal growth factor (EGF) with hydroxyapatite powder in the socket. Histological evaluation for bone formation, bone cell and inflammatory cell count with histomorphometry of bone trabeculae percentage had been done to all study groups and for three periods (5,14 &28 days). Results: Epidermal growth factor with hydroxyapatite group showed early bone formation, more bone cell count, and less inflammatory cell infiltration in comparison to the HAP group and control at periods (5,14&28 days) and with a statistically significant difference (p<0.05). Bone trabeculae percentage was recorded to be high in the HAP&EGF group that filled the socket hole at (14 ,28 days) intervals in comparison to hydroxyapatite and control group. Complete re-epithelialization was observed only in the EGF&HAP group. Conclusions: Both the HAP&EGF group and the hydroxyapatite group show bone formation and good socket healing, but the EGF&HAP group showed to be faster in filling of boney socket hole with complete epithelization than hydroxyapatite group, therefor using EGF with HAP is more efficient and suggested the material of choice used for socket healing.

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“…28 In contrast, another study in humans found a faster reduction in the wound size of open sockets after a single honey treatment directly after tooth extraction. 26 A human double-blinded clinical trial observed lower pain scores and less painkiller intake after tooth extraction with a single intra-socket application of honey before surgical closure. 27 No side effects or allergic reactions to MGH were noticed in any of the patients enrolled in these studies.…”

Section: Introductionmentioning

confidence: 99%

“…[18][19][20][21] Most studies have investigated the use of MGH in skin wounds; however, experimental studies in animals and recent clinical studies in human patients showed beneficial effects of topical intra-socket use of MGH after tooth extraction. [22][23][24][25][26][27][28] An experimental study in rabbits and one in rats was conducted, whereby honey was applied into the socket after extraction and then surgically closed by suturing. 22,23 In the control group, the socket was left to fill with a blood clot and was then closed surgically.…”

Section: Introductionmentioning

confidence: 99%

Intra-socket application of medical-grade honey after tooth extraction attenuates inflammation and promotes healing in cats

Pleeging

Rooster

Wijk

et al. 2022

Journal of Feline Medicine and Surgery

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Objectives Dental diseases are a major problem in cats and often necessitate tooth extraction. Medical-grade honey (MGH) has antimicrobial and wound-healing properties, and therefore the aim of this study was to investigate whether intra-socket application improved healing after tooth extraction. It was postulated that applying MGH would reduce inflammation, improve the viability of the surgical flap and enhance healing following tooth extraction. Methods A prospective randomised controlled trial was performed in client-owned cats undergoing bilateral tooth extractions of the same element of the canine or (pre)molar tooth. A split-mouth design was used in which every animal served as its own control. After surgical extraction of the elements, the sockets on one side were filled with an MGH-based ointment (L-Mesitran Soft), whereas the contralateral side received no treatment (control). A mucoperiosteal flap was used on both sides, and simple interrupted monofilament sutures were placed. No antimicrobial drugs were administered. Clinical parameters (inflammation/redness, flap viability and wound healing) were subjectively analysed on days 3 and 7 post-extraction by a veterinarian blinded to the treatment. Results Twenty-one cats were included. MGH significantly decreased signs of inflammation ( P <0.01), improved mucoperiosteal flap viability ( P <0.01) and promoted wound healing ( P = 0.01), at both time points. MGH was easy to apply and there were no adverse events. Conclusions and relevance Intra-socket application of MGH after tooth extraction positively affects the surgical wound, as it reduces redness, improves flap viability and enhances wound healing. Applying MGH represents a potent adjuvant therapy to support intra-oral wound healing after tooth extraction.

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Evaluation of the effect of honey on the healing of tooth extraction wounds in 4- to 9-year-old children

Cited by 12 publications

References 2 publications

Evaluation of post-extraction healing after atraumatic axial tooth extraction using Benex system II versus conventional extraction: Randomized control trial

Evaluation of post-extraction healing after atraumatic axial tooth extraction using Benex system II versus conventional extraction: Randomized control trial

Histological and Histomorphometric Evaluation of Socket Healing After Application of Epidermal Growth Factor with synthetic hydroxyapatite powder in Rats

Intra-socket application of medical-grade honey after tooth extraction attenuates inflammation and promotes healing in cats

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